Dr Timothea Toulopoulou  B.A. (Hons) M.Sc. Ph.D. CPsychol
Visiting Senior Lecturer in Psychosis

email	contact this person
tel	020 7848 0061
fax	0207 701 9044
address	Institute of Psychiatry Box  P063 De Crespigny Park London United Kingdom, SE5 8AF
location	M 5.23 Main Wing
departments	Psychological Medicine Psychosis Studies
also	General Psychiatry

biography

Dr Timothea Toulopoulou earned her Ph.D. (University of London, UK) in the field of neuropsychology, studying the Neuropsychology of Schizophrenia, focusing in particular on episodic memory and executive processing. Her main interests lie in exploring putative cognitive endophenotypes for schizophrenia. Dr Toulopoulou was awarded several International Young Scientist Awards and numerous travel grants, as well as a Canon Foundation in Europe Research Fellowship to work in Hamamatsu Medical School, Japan. In 2005 she received a two-year Young Investigator Award from the National Alliance of Research on Schizophrenia and Affective Disorders (USA) that allowed her to work at Harvard Medical School, USA. Currently, Dr Toulopoulou is the Lead Scientist for the genes and cognition work package of the European Commission FP6 Programme funded study of twins affected by schizophrenia: The European Twin Study Network on Schizophrenia(EUTwinsS). EUTwinsS is the largest study of twins affected by schizophrenia in the world involving collaboration between nine mental health research centres in six European countries: Germany, the UK, The Netherlands, Spain, Hungary and Switzerland. The consortium is a multidisciplinary network that uses neuroimaging, neurophysiology and neurocognitive methods, as well as molecular and behavioural genetics studying twins with schizophrenia.

activities and interests

Endophenotypes, genetic risk factors, schizophrenia, cognition, memory, executive function, twin and family study design, genes and cognition

teaching activities

Supervision

PhD Supervisor (Institute of Psychiatry, King’s College London, University of London) on identifying endophenotypes in schizophrenia

MSc Neuroscience (Institute of Psychiatry, King’s College London, University of London), Project Supervisor

BSc Psychology (Brunel University), Project Supervisor

BSc Neuroscience and Neuropsychology (King’s College London, University of London), Project Supervisor

publications

PEER REVIEWED PUBLICATIONS

Toulopoulou T, Goldberg TE, Rebollo Mesa I, Picchioni M, Rijsdijk F, Stahl D, Cherny S S, Sham P, Faraone SV, Tsuang M, Weinberger DR, Seidman LJ, Murray R M (2010) Impaired intellect and memory: a missing link between genetic risk and schizophrenia? Arch Gen Psychiatry. 2010;67(9):905-913

Owens SF, Rodger AK, Picchioni MM., Rijsdijk FV, Stahl D, Vassos E, Collier DA, Murray, RM, Toulopoulou T (2010) Genetic overlap between episodic memory deficits and schizophrenia – results from The Maudsley Twin Study. Psychological Medicine 2010 May 12:1-12. [Epub ahead of print]

Vassos E, Bramon E, Picchioni M, Walshe M, Filbey FM, Kravariti E, McDonald C Murray RM, Collier DA, Toulopoulou T (2010) Evidence of association of KIBRA genotype with episodic memory in families of psychotic patients and controls. Journal of Psychiatric Research. J Psychiatr Res. 2010 Feb 23 [Epub ahead of print]

Owens SF, Rijsdijk FV, Picchioni MM, Stahl D, Nenadic I, Murray R, Toulopoulou T. Genetic overlap between schizophrenia and selective components of executive function. Schizophrenia Research. In Press

Waters-Metenier SL, Toulopoulou T Putative diffusion tensor neuroimaging endophenotypes in Schizophrenia: a review of the early evidence. Future Neurology. Accepted

Waters-Metenier SL, Toulopoulou T Qualifying brain functional MRI parameters as endophenotypes in schizophrenia. Future Neurology. Accepted

Waters-Metenier SL, Toulopoulou T Putative structural neuroimaging endophenotypes in Schizophrenia: a comprehensive review of the current evidence. Future Neurology. Accepted

Rebollo-Mesa I, Picchioni M, Shaikh M; Bramon E, Murray R, Toulopoulou T COMT (Val158/108Met) genotype moderates the impact of antipsychotic medication on verbal IQ in twins with schizophrenia. Psychiatric Genetics. Accepted

Ettinger U, Schmechtig A, Toulopoulou T, Borg C, Orrells C, Owens S, Matsumoto K, van Haren NE, Hall MH, Kumari V, McGuire PK, Murray RM, Picchioni M. Prefrontal and Striatal Volumes in Monozygotic Twins Concordant and Discordant for Schizophrenia. Schizophr Bull. 2010 Jun 10. [Epub ahead of print]

Aas M, Dazzan P, Mondelli V, Toulopoulou T, Reichenberg A, Di Forti M, Fisher HL, Handley R, Hepgul N, Marques T, Miorelli A, Taylor H, Russo M, Wiffen B, Papadopoulos A, Aitchison KJ, Morgan C, Murray RM, Pariante CM. Abnormal cortisol awakening response predicts worse cognitive function in patients with first-episode psychosis. Psychol Med. 2010 Jun 9:1-14. [Epub ahead of print]

Shaikh M, Hall MH, Schulze K, Dutt A, Walshe M, Williams I, Constante M, Picchioni M, Toulopoulou T, Collier D, Rijsdijk F, Powell J, Arranz M, Murray RM, Bramon E. Do COMT, BDNF and NRG1 polymorphisms influence P50 sensory gating in psychosis? Psychol Med. 2010 Jan 27:1-14. [Epub ahead of print]

Steinberg S, Mors O, Børglum AD, Gustafsson O, Werge T, Mortensen PB, Andreassen OA, Sigurdsson E, Thorgeirsson TE, Böttcher Y, Olason P, Ophoff RA, Cichon S, Gudjonsdottir IH, Pietiläinen OP, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Athanasiu L, Suvisaari J, Lonnqvist J, Paunio T, Hartmann A, Jürgens G, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Breuer R, Möller HJ, Giegling I, Glenthøj B, Rasmussen HB, Mattheisen M, Bitter I, Réthelyi JM, Sigmundsson T, Fossdal R, Thorsteinsdottir U, Ruggeri M, Tosato S, Strengman E; GROUP, Kiemeney LA, Melle I, Djurovic S, Abramova L, Kaleda V, Walshe M, Bramon E, Vassos E, Li T, Fraser G, Walker N, Toulopoulou T, Yoon J, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Jönsson EG, Terenius L, Agartz I, Petursson H, Nöthen MM, Rietschel M, Peltonen L, Rujescu D, Collier DA, Stefansson H, St Clair D, Stefansson K. Expanding the range of ZNF804A variants conferring risk of psychosis. Mol Psychiatry. 2010 Jan 5. [Epub ahead of print]

Borgwardt SJ, Picchioni MM, Ettinger U, Toulopoulou T, Murray R, McGuire PK. Regional Gray Matter Volume in Monozygotic Twins Concordant and Discordant for Schizophrenia. Biol Psychiatry. [Epub ahead of print]

Hall MH, Taylor G, Sham P, Schulze K, Rijsdijk F, Picchioni M, Toulopoulou T, Ettinger U, Bramon E, Murray RM, Salisbury DF. The Early Auditory Gamma-Band Response Is Heritable and a Putative Endophenotype of Schizophrenia. Schizophr Bull. 2009 Nov 27. [Epub ahead of print]

Prata DP, Mechelli A, Picchioni MM, Fu CH, Toulopoulou T, Bramon E, Walshe M, Murray RM, Collier DA, McGuire P. Altered effect of dopamine transporter 3’UTR VNTR genotype on prefrontal and striatal function in schizophrenia.Arch Gen Psychiatry. 2009 Nov;66(11):1162-72.

Picchioni MM, Walshe M, Toulopoulou T, McDonald C, Taylor M, Waters-Metenier S, Bramon E, Regojo A, Murray RM, Rijsdijk F. Genetic modelling of childhood social development and personality in twins and siblings with schizophrenia. Psychol Med. 2009 Oct 29:1-12.

Ingason A, Rujescu D, Cichon S, Sigurdsson E, Sigmundsson T, Pietiläinen OP, Buizer-Voskamp JE, Strengman E, Francks C, Muglia P, Gylfason A, Gustafsson O, Olason PI, Steinberg S, Hansen T, Jakobsen KD, Rasmussen HB, Giegling I, Möller HJ, Hartmann A, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Bramon E, Kiemeney LA, Franke B, Murray R, Vassos E, Toulopoulou T, Mühleisen TW, Tosato S, Ruggeri M, Djurovic S, Andreassen OA, Zhang Z, Werge T, Ophoff RA; GROUP Investigators, Rietschel M, Nöthen MM, Petursson H, Stefansson H, Peltonen L, Collier D, Stefansson K, Clair DM. Copy number variations of chromosome 16p13.1 region associated with schizophrenia Mol Psychiatry. 2009 Sep 29. [Epub ahead of print].

Prata DP, Mechelli A, Fu CH, Picchioni M, Toulopoulou T, Bramon E, Walshe M, Murray RM, Collier DA, McGuire P. Epistasis between the DAT 3’ UTR VNTR and the COMT Val158Met SNP on cortical function in healthy subjects and patients with schizophrenia. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13600-5. Epub 2009 Jul 28.

Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Børglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Böttcher Y, Olesen J, Breuer R, Möller HJ, Giegling I, Rasmussen HB, Timm S, Mattheisen M, Bitter I, Réthelyi JM, Magnusdottir BB, Sigmundsson T, Olason P, Masson G, Gulcher JR, Haraldsson M, Fossdal R, Thorgeirsson TE, Thorsteinsdottir U, Ruggeri M, Tosato S, Franke B, Strengman E, Kiemeney LA; Genetic Risk and Outcome in Psychosis (GROUP), Melle I, Djurovic S, Abramova L, Kaleda V, Sanjuan J, de Frutos R, Bramon E, Vassos E, Fraser G, Ettinger U, Picchioni M, Walker N, Toulopoulou T, Need AC, Ge D, Yoon JL, Shianna KV, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Carracedo A, Arango C, Costas J, Jönsson EG, Terenius L, Agartz I, Petursson H, Nöthen MM, Rietschel M, Matthews PM, Muglia P, Peltonen L, St Clair D, Goldstein DB, Stefansson K, Collier DA. Common variants conferring risk of schizophrenia. Nature. 2009 Aug 6;460(7256):744-7. Epub 2009 Jul

Zanelli J, MacCabe J, Toulopoulou T, Walshe M, McDonald C, Murray R. Neuropsychological correlates of eye movement abnormalities in schizophrenic patients and their unaffected relatives. Psychiatry Res. 2009 Aug 15;168(3):193-7. Epub 2009 Jun 21.

Costafreda SG, Fu CH, Picchioni M, Kane F, McDonald C, Prata DP, Kalidindi S, Walshe M, Curtis V, Bramon E, Kravariti E, Marshall N, Toulopoulou T, Barker GJ, David AS, Brammer MJ, Murray RM, McGuire PK. Increased inferior frontal activation during word generation: a marker of genetic risk for schizophrenia but not bipolar disorder? Hum Brain Mapp. 2009 Oct;30(10):3287-98.

Quraishi S, Walshe M, McDonald C, Schulze K, Kravariti E, Bramon E, Morris RG, Murray RM, Toulopoulou T. Memory functioning in familial bipolar I disorder patients and their relatives. Bipolar Disord. 2009 Mar;11(2):209-14.

Kanaan R, Barker G, Brammer M, Giampietro V, Shergill S, Woolley J, Picchioni M, Toulopoulou T, McGuire P. White matter microstructure in schizophrenia: effects of disorder, duration and medication. Br J Psychiatry. 2009 Mar;194 (3):236-42.

Prata DP, Mechelli A, Fu CH, Picchioni M, Kane F, Kalidindi S, McDonald C, Howes O, Kravariti E, Demjaha A, Toulopoulou T, Diforti M, Murray RM, Collier DA, McGuire PK. Opposite effects of catechol-O-methyltransferase Val158Met on cortical function in healthy subjects and patients with schizophrenia. Biol Psychiatry. 2009 Mar 15;65(6):473-80. Epub 2008 Dec 3.

Rujescu D, Ingason A, Cichon S, Pietiläinen OP, Barnes MR, Toulopoulou T, Picchioni M, Vassos E, Ettinger U, Bramon E, Murray R, Ruggeri M, Tosato S, Bonetto C, Steinberg S, Sigurdsson E, Sigmundsson T, Petursson H, Gylfason A, Olason PI, Hardarsson G, Jonsdottir GA, Gustafsson O, Fossdal R, Giegling I, Möller HJ, Hartmann A, Hoffmann P, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Andreassen OA, Djurovic S, Hansen T, Werge T, Melle I, Kiemeney LA, Franke B, Buizer-Voskamp JE, Ophoff RA; GROUP Investigators, Rietschel M, Nöthen MM, Stefansson K, Peltonen L, St Clair D, Stefansson H, Collier DA. Disruption of the neurexin 1 gene is associated with schizophrenia. Hum Mol Genet. 2008 Oct 22. [Epub ahead of print]

Prata DP, Mechelli A, Fu CH, Picchioni M, Kane F, Kalidindi S, McDonald C, Kravariti E, Toulopoulou T, Miorelli A, Murray R, Collier DA, McGuire PK. Effect of disrupted-in-schizophrenia-1 on pre-frontal cortical function.
Mol Psychiatry. 2008 Oct;13(10):915-7, 909.

Prata DP, Mechelli A, Fu CH, Picchioni M, Kane F, Kalidindi S, McDonald C, Kravariti E, Toulopoulou T, Miorelli A, Murray R, Collier DA, McGuire PK. The DISC1 Ser704Cys polymorphism is associated with prefrontal function in healthy individuals. Mol Psychiatry. 2008 Oct;13(10):909.

Stefansson H, Rujescu D, Cichon S, Pietiläinen OP, Ingason A, Steinberg S, Fossdal R, Sigurdsson E, Sigmundsson T, Buizer-Voskamp JE, Hansen T, Jakobsen KD, Muglia P, Francks C, Matthews PM, Gylfason A, Halldorsson BV, Gudbjartsson D, Thorgeirsson TE, Sigurdsson A, Jonasdottir A, Jonasdottir A, Bjornsson A, Mattiasdottir S, Blondal T, Haraldsson M, Magnusdottir BB, Giegling I, Möller HJ, Hartmann A, Shianna KV, Ge D, Need AC, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Paunio T, Toulopoulou T, Bramon E, Di Forti M, Murray R, Ruggeri M, Vassos E, Tosato S, Walshe M, Li T, Vasilescu C, Mühleisen TW, Wang AG, Ullum H, Djurovic S, Melle I, Olesen J, Kiemeney LA, Franke B, Sabatti C, Freimer NB, Gulcher JR, Thorsteinsdottir U, Kong A, Andreassen OA, Ophoff RA, Georgi A, Rietschel M, Werge T, Petursson H, Goldstein DB, Nöthen MM, Peltonen L, Collier DA, St Clair D, Stefansson K, Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I; Genetic Risk and Outcome in Psychosis (GROUP). Large recurrent microdeletions associated with schizophrenia. Nature. 2008 Sep 11;455(7210):232-6.

Mechelli A, Prata DP, Fu CH, Picchioni M, Kane F, Kalidindi S, McDonald C, Demjaha A, Kravariti E, Toulopoulou T, Murray R, Collier DA, McGuire PK. The effects of neuregulin1 on brain function in controls and patients with schizophrenia and bipolar disorder. Neuroimage. 2008 Aug 15;42(2):817-26.

Argyropoulos SV, Landau S, Kalidindi S, Toulopoulou T, Castle DJ, Murray RM, Picchioni MM. Twins discordant for schizophrenia: psychopathology of the non-schizophrenic co-twins. Acta Psychiatr Scand. 2008 Sep;118(3):214-9.

Filbey FM, Toulopoulou T, Morris RG, McDonald C, Bramon E, Walshe M, Murray RM. Selective attention deficits reflect increased genetic vulnerability to schizophrenia. Schizophr Res. 2008 Apr;101(1-3):169-75.

Li T, Ma X, Hu X, Wang Y, Yan C, Meng H, Liu X, Toulopoulou T, Murray RM, Collier DA. PRODH gene is associated with executive function in schizophrenic families. Am J Med Genet B Neuropsychiatr Genet. 2008 Jul 5;147B(5):654-7.

Chan RC, Shum D, Toulopoulou T, Chen EY. Assessment of executive functions: review of instruments and identification of critical issues. Arch Clin Neuropsychol. 2008 Mar;23(2):201-16.

Nagai M, Tsuchiya KJ, Toulopoulou T, Takei N. Poor mental health associated with job dissatisfaction among school teachers in Japan. J Occup Health. 2007 Nov;49(6):515-22.

Toulopoulou T, Picchioni M, Rijsdijk F, Hua-Hall M, Ettinger U, Sham P, Murray R. Substantial genetic overlap between neurocognition and schizophrenia: genetic modeling in twin samples. Arch Gen Psychiatry. 2007 Dec;64(12):1348-55.

Rosa A, Picchioni MM, Kalidindi S, Loat CS, Knight J, Toulopoulou T, Vonk R, van der Schot AC, Nolen W, Kahn RS, McGuffin P, Murray RM, Craig IW. Differential methylation of the X-chromosome is a possible source of discordance for bipolar disorder female monozygotic twins. Am J Med Genet B Neuropsychiatr Genet. 2007 Oct 22; [Epub ahead of print]

Birkett P, Sigmundsson T, Sharma T, Toulopoulou T, Griffiths TD, Reveley A, Murray R. Executive function and genetic predisposition to schizophrenia-the Maudsley family study. Am J Med Genet B Neuropsychiatr Genet. 2007 Sep 12; [Epub ahead of print]

Toulopoulou T, Chua SE, Lam I, Cheung V, Murray RM, David AS. Evidence of normal hearing laterality in familial schizophrenic patients and their relatives. Am J Med Genet B Neuropsychiatr Genet. 2007 Aug 22; [Epub ahead of print]

Birkett P, Sigmundsson T, Sharma T, Toulopoulou T, Griffiths TD, Reveley A, Murray R. Reaction time and sustained attention in schizophrenia and its genetic predisposition. Schizophr Res. 2007 Sep;95(1-3):76-85. Epub 2007 Jul 13.

Hall MH, Rijsdijk F, Picchioni M, Schulze K, Ettinger U, Toulopoulou T, Bramon E, Murray RM, Sham P. Substantial shared genetic influences on schizophrenia and event-related potentials. Am J Psychiatry. 2007 May;164(5):804-12.

Ettinger U, Picchioni M, Landau S, Matsumoto K, van Haren NE, Marshall N, Hall MH, Schulze K, Toulopoulou T, Davies N, Ribchester T, McGuire PK, Murray RM. Magnetic resonance imaging of the thalamus and adhesio interthalamica in twins with schizophrenia. Arch Gen Psychiatry. 2007 Apr;64(4):401-9.

Dempster EL, Toulopoulou T, McDonald C, Bramon E, Walshe M, Wickham H, Sham PC, Murray RM, Collier DA. Episodic memory performance predicted by the 2bp deletion in exon 6 of the "alpha 7-like" nicotinic receptor subunit gene. Am J Psychiatry. 2006 Oct;163(10):1832-4.

Dikeos DG, Wickham H, McDonald C, Walshe M, Sigmundsson T, Bramon E, Grech A, Toulopoulou T, Murray R, Sham PC. Distribution of symptom dimensions across Kraepelinian divisions. Br J Psychiatry. 2006 Oct;189:346-53.

Ettinger U, Picchioni M, Hall MH, Schulze K, Toulopoulou T, Landau S, Crawford TJ, Murray RM. Antisaccade performance in monozygotic twins discordant for schizophrenia: the Maudsley twin study. Am J Psychiatry. 2006 Mar;163(3):543-5.

Toulopoulou T, Quraishi S, McDonald C, Murray RM. The Maudsley Family Study: premorbid and current general intellectual function levels in familial bipolar I disorder and schizophrenia. J Clin Exp Neuropsychol. 2006 Feb;28(2):243-59.

Kravariti E, Toulopoulou T, Mapua-Filbey F, Schulze K, Walshe M, Sham P, Murray RM, McDonald C. Intellectual asymmetry and genetic liability in first-degree relatives of probands with schizophrenia. Br J Psychiatry. 2006 Feb;188:186-7.

Takagai S, Kawai M, Tsuchiya KJ, Mori N, Toulopoulou T, Takei N. Increased rate of birth complications and small head size at birth in winter-born male patients with schizophrenia. Schizophr Res. 2006 Apr;83(2-3):303-5. Epub 2006 Jan 18.

Picchioni MM, Toulopoulou T, Landau S, Davies N, Ribchester T, Murray RM. Neurological abnormalities in schizophrenic twins. Biol Psychiatry. 2006 Feb 15;59(4):341-8. Epub 2005 Sep 19.

Rijsdijk FV, van Haren NE, Picchioni MM, McDonald C, Toulopoulou T, Hulshoff Pol HE, Kahn RS, Murray R, Sham PC. Brain MRI abnormalities in schizophrenia: same genes or same environment? Psychol Med. 2005 Oct;35(10):1399-409.

Toulopoulou T, Mapua-Filbey F, Quraishi S, Kravariti E, Morris RG, McDonald C, Walshe M, Bramon E, Murray RM. Cognitive performance in presumed obligate carriers for psychosis. Br J Psychiatry. 2005 Sep;187:284-5.

Bramon E, Walshe M, McDonald C, Martín B, Toulopoulou T, Wickham H, van Os J, Fearon P, Sham PC, Fañanás L, Murray RM. Dermatoglyphics and Schizophrenia: a meta-analysis and investigation of the impact of obstetric complications upon a-b ridge count.Schizophr Res. 2005 Jun 15;75(2-3):399-404.

Sekine Y, Takei N, Suzuki K, Nakamura K, Tsuchiya KJ, Takebayashi K, Toulopoulou T, Mori N. Effective adjunctive use of pergolide with quetiapine for cognitive impairment and negative symptoms in schizophrenia. J Clin Psychopharmacol. 2005 Jun;25(3):281-3.

Dempster E, Toulopoulou T, McDonald C, Bramon E, Walshe M, Filbey F, Wickham H, Sham PC, Murray RM, Collier DA. Association between BDNF val66 met genotype and episodic memory. Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 5;134(1):73-5.

Toulopoulou T, Grech A, Morris RG, Schulze K, McDonald C, Chapple B, Rabe-Hesketh S, Murray RM. The relationship between volumetric brain changes and cognitive function: a family study on schizophrenia. Biol Psychiatry. 2004 Sep 15;56(6):447-53.

Toulopoulou T, Murray RM. Verbal memory deficit in patients with schizophrenia: An important future target for treatment. Expert Review of Neurotherapeutics. 2004 4(1):43-52.

Toulopoulou T, Takei N. Utility of neuropsychological tests to genetic studies of schizophrenia. Japanese Journal of Molecular Psychiatry. 2004 4(1):48-55.

Chapple B, Grech A, Sham P, Toulopoulou T, Walshe M, Schulze K, Morgan K, Murray RM, McDonald C. Normal cerebral asymmetry in familial and non-familial schizophrenic probands and their unaffected relatives. Schizophr Res. 2004 Mar 1;67(1):33-40.

Toulopoulou T, Rabe-Hesketh S, King H, Murray RM, Morris RG. Episodic memory in schizophrenic patients and their relatives. Schizophr Res. 2003 Oct 1;63(3):261-71.

Schulze K, McDonald C, Frangou S, Sham P, Grech A, Toulopoulou T, Walshe M, Sharma T, Sigmundsson T, Taylor M, Murray RM. Hippocampal volume in familial and nonfamilial schizophrenic probands and their unaffected relatives. Biol Psychiatry. 2003 Apr 1;53(7):562-70.

Toulopoulou T, Morris RG, Rabe-Hesketh S, Murray RM. Selectivity of verbal memory deficit in schizophrenic patients and their relatives. Am J Med Genet B Neuropsychiatr Genet. 2003 Jan 1;116(1):1-7.

McDonald C, Grech A, Toulopoulou T, Schulze K, Chapple B, Sham P, Walshe M, Sharma T, Sigmundsson T, Chitnis X, Murray RM. Brain volumes in familial and non-familial schizophrenic probands and their unaffected relatives. Am J Med Genet. 2002 Aug 8;114(6):616-25.

Rabe-Hesketh S, Toulopoulou T, Murray RM. Multilevel modeling of cognitive function in schizophrenic patients and their first-degree relatives. Multivariate Behavioral Research. 2001 (2):279-289.




BOOK CHAPTERS

Picchioni M, Toulopoulou T. Genetic Determinants of the Vulnerability to Psychosis: Findings from Twin Studies. Maudsley Monographs. 2010. Routledge, London. In Press

Toulopoulou T, Mapua-Filbey F, Kravariti E. Neuropsychological impairments in patients with schizophrenia and their unaffected relatives. In Colm McDonald (Editor). Maudsley Monographs: The Maudsley Family Study of Psychosis - a quest for intermediate phenotypes. 2008. Routledge, London.

Chan RCK, Toulopoulou T. Fractionation of executive function in schizophrenia: relationships to clinical and neurological manifestations. In Douglas P French (Editor-in-Chief), 1-39. Schizophrenic psychology. New research. 2006. Nova Science Publishers, Inc. Hauppauge, New York, USA.

last updated: Thursday, August 11, 2011