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Dr Louise Arseneault  

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emailcontact this person
tel020 7848 0647
fax020 7848 0866
addressBox Number P080
location C1.15
MRC, SGDP Centre
departmentsSocial, Genetic and Developmental Psychiatry (IRG)
Social, Genetic and Developmental Psychiatry Centre (MRC)


My research focuses on the study of harmful behaviours such as violence and substance dependence, their developmental origins, their inter-connections with mental health, and their consequences for victims. In the early stages of my career, I examined harmful behaviours as a developmental outcome, primarily in adolescents and in adults. Over time, my focus broadened to include harmful behaviours as causes of psychiatric disorders. I am currently taking a developmental approach to investigate how the consequences of violence begin in childhood by studying bullying victimisation and child maltreatment. My research aims are to answer questions relevant to psychology and psychiatry by harnessing and combining 3 different research approaches: developmental research, epidemiological methods and genetically-sensitive designs. My work incorporates biological as well as social measurements.

Discipline(s): Biomedical Science, developmental psychology and epidemiology


Houts, R.M., Caspi, A., Pianta, R.C., Arseneault, L., & Moffitt, T.E. (2010). The challenging pupil in the classroom: Child effects on teachers. Psychological Science.

Sugden, K., Arseneault, L., Harrington, H., Moffitt, T.E., Williams, B., & Caspi, A. (2010). Variation in the serotonin transporter gene moderates the development of emotional problems among children following bullying victimization. Journal of the American Academy of Child and Adolescent Psychiatry, 49, 830-840.

Danese, A., Caspi, A., Williams, B., Ambler, A., Sugden, K., Mika, J., Werts, H., Freeman, J., Pariante, C.M., Moffitt, T.E., & Arseneault, L. (2010). Biological embedding of stress through inflammation processes in childhood. Molecular Psychiatry.

Harley, M., Kelleher, I., Lynch, F., Clarke, M., Arseneault, L., Connor, D., Fitzpatrick, C., & Cannon, M. (2010). The role of childhood trauma in mediating the association between cannabis use and psychotic symptoms in adolescence. Psychological Medicine, 40, 1627-1634.

Bowes, L., Maughan, B., Caspi, A., Moffitt, T.E., & Arseneault, L. (2010). Families promote emotional and behavioural resilience to bullying: Evidence of an environmental effect. Journal of Child Psychology and Psychiatry, 51, 809-817

Arseneault, L., Bowes, L., Shakoor, S. (2010). Bullying victimisation in youths and mental health problems: “Much ado about nothing”? Psychological Medicine, 40, 717-729.

Polanczyk, G., Moffitt, T., Arseneault, L., Cannon, M., Ambler, A., Keefe, R.S.E., Houts, R., Odgers, C.L., & Caspi, A. (2010). Childhood psychotic symptoms share etiological and clinical features with adult schizophrenia: Results from a representative birth cohort. Archives of General Psychiatry, 67, 328-338.

Vitaro, F., Brendgen, M., & Arseneault, L. (2009). The discordant MZ-twin method: One step closer to the Holy Grail. International Journal of Behavioral Development, 33, 376-382.

Bowes, L., Arseneault, L., Maughan, B., Taylor, A., Caspi, A., & Moffitt, TE (2009). School, neighborhood and family factors are associated with children’s bullying involvement: A nationally-representative longitudinal study. Journal of the American Academy of Child and Adolescent Psychiatry, 48, 545-553.

Ouellet-Morin, I., Dionne, G., Pérusse, D., Lupien, S.J., Arseneault, L., Barr, R.G., Tremblay, R. E., & Boivin, M. (2009). Daytime cortisol secretion in 6 month-old twins: Genetic and environmental contributions as a function of early familial adversity. Biological Psychiatry, 65, 409-416.

Kelleher, I., Harley, M., Lynch, F., Arseneault, L., Fitzpatrick, C., & Cannon, M. (2008). Associations between childhood trauma, bullying and psychotic symptoms among a school-based adolescent sample. British Journal of Psychiatry, 193, 378-382.

Barker, E.D., Boivin, M., Brendgen, M., Fontaine, N., Arseneault, L., Vitaro, F., Bissonnette, C., & Tremblay, R.E. (2008). Predictive validity and early predictors of trajectories in preschool. Archives of General Psychiatry, 65, 1185-1192.

Barker, E.D., Arseneault, L., Brendgen, M., Fontaine, N., & Maughan, B. (2008). Joint development of bullying and victimization in adolescence: Relationships to delinquency and self-harm. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 1030-1038.

Ouellet-Morin, I., Boivin, M., Dionne, G., Lupien, S.J., Arseneault, L., Barr, R.G., Pérusse, D., & Tremblay, R. E. (2008). Variations in heritability of cortisol reactivity to stress as a function of early familial adversity among 19 month-old twins. Archives of General Psychiatry, 65, 211-218.

Arseneault, L., Milne, B.J., Taylor, A., Adams, F., Delgado, K., Caspi, A., Moffitt, T.E. (2008). Being bullied as an environmentally mediated contributing factor to children’s internalizing problems: A study of twins discordant for victimization. Archives of Pediatrics & Adolescent Medicine, 162, 145-150.

Moffitt, T.E., Arseneault, L., Jaffee, S.R., Kim-Cohen, J., Koenen, K.C., Odgers, C.L., Slutske, W., & Viding, E. (2008). DSM-V Conduct Disorder: Research needs for an evidence base. Journal of Child Psychology and Psychiatry, 49, 3-33.

Ball, H.A., Arseneault, L., Taylor, A., Maughan, B., Caspi, A., & Moffitt, T.E. (2008). Genetic and environmental influences on victims, bullies and bully-victims in childhood. Journal of Child Psychology and Psychiatry, 49, 104-112.

Arseneault, L., Walsh, E., Trzesniewski, K., Newcombe, R., Caspi, A., & Moffitt, T.E. (2006). Bullying victimization uniquely contributes to adjustment problems in young children: A nationally representative cohort study. Pediatrics, 118, 130-138.

Lacourse, E., Nagin, D.S., Vitaro, F., Côté, S., Arseneault, L., & Tremblay, R.E. (2006). Prediction of early onset deviant peer group affiliation: A 12 year longitudinal study. Archives of General Psychiatry, 63, 562-568.

Silver, E., Arseneault, L., Langley, J., Caspi, A., & Moffitt, T.E. (2005). Mental disorder and violent victimization in a total birth cohort. American Journal of Public Health, 95, 2015-2021.

Arseneault, L., Kim-Cohen, J., Taylor, A., Caspi, A., & Moffitt, T. E. (2005). Psychometric evaluation of 5- and 7-year-old children’s self-reports of conduct problems. Journal of Abnormal Child Psychology, 33, 537-550.

Kim-Cohen, J., Arseneault, L., Caspi, A., Polo Tomas, M., Taylor, A., & Moffitt, T. E. (2005). Validity of DSM-IV conduct disorder in 4½-5-year-old children: A longitudinal epidemiological study. American Journal of Psychiatry, 162, 1108-1117.

Caspi, A., Moffitt, T. E., Cannon, M., McClay, J., Murray, R., Harrington, H., Taylor, A., Arseneault, L., Williams, B., Braithwaite, A., Poulton, R., & Craig, I. (2005). Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the COMT gene. Biological Psychiatry, 57, 1117-1127.

Caspi, A., Moffitt, T.E., Morgan, J., Rutter, M., Taylor, A., Arseneault, L., Tully, L., Jacobs, C., Kim-Cohen, J., & Polo-Tomas, M. (2004). Maternal expressed emotion predicts children’s antisocial behavior problems: Using MZ-twin differences to identify environmental effects on behavioral development. Developmental Psychology, 40, 149-161.

Tully, L.A., Arseneault, L., Caspi, A., Moffitt, T.E., & Morgan, J. (2004). Does maternal warmth moderate the effects of birth weight on twins’ attention-deficit/hyperactivity disorder (ADHD) symptoms and low IQ? Journal of Consulting and Clinical Psychology, 72, 218-226.

Arseneault, L., Cannon, M., Witton, J., & Murray, R. (2004). The causal association between cannabis and psychosis: An examination of the evidence. British Journal of Psychiatry, 184, 110-117.

Arseneault, L., Cannon, M., Moffitt, T.E., Caspi, A., Poulton, R., & Murray, R. (2004). Childhood origins of violent behaviour among adults with schizophreniform disorder. British Journal of Psychiatry, 183, 520-525.

Sluyter, F., Arseneault, L., Moffitt, T.E., Veenema, A.H., de Boer, S., & Koolhaas, J.M. (2003). Toward an animal model for antisocial behavior: Parallels between mice and humans. Behavior Genetics, 33, 563-574.

Arseneault, L., Moffitt, T.E., Caspi, A., Taylor, A., Rijsdijk, F.V., Jaffee, S., Ablow, J.C., & Measelle, J.R. (2003). Strong genetic effects on cross-situational antisocial behavior among 5-year-old children according to mothers, teachers, examiner-observers, and twins’ self-reports. Journal of Child Psychology and Psychiatry, 44, 832-848.

Arseneault, L., Cannon, M., Poulton, R., Murray, R.M., Caspi, A., & Moffitt, T.E. (2002). Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study. British Medical Journal, 325, 1212-1213.

Arseneault, L., Moffitt, T.E., Caspi, A., & Taylor, A. (2002). The targets of violence committed by young offenders with alcohol dependence, marijuana dependence, and schizophrenia-spectrum disorders: Findings from a birth cohort. Criminal Behavior and Mental Health, 12, 155-168.

Arseneault, L., Tremblay, R.E., Boulerice, B., & Saucier, J.-F. (2002). Obstetrical complications and adolescent violent behaviors: Testing two developmental pathways. Child Development, 73, 496-508.

Arseneault, L., Moffitt, T.E., Caspi, A., Taylor, P.J., & Silva, P.A. (2000). Mental disorders and violence in a total birth cohort: Results from the Dunedin Study. Archives of General Psychiatry, 57, 979-986.

last updated: Tuesday, January 28, 2014