Find people 

Professor Matthew Hotopf  BSc MBBS MSc PhD MRCPsych
Professor of General Hospital Psychiatry
Head of Section: General Hospital Psychiatry
Theme Lead: Analytic Methods Cross Cutting Theme of the SLAM/KCL NIHR Biomedical Research Centre
Director: Nucleus of SLAM/KCL NIHR Biomedical Research Centre

staff photo
emailcontact this person
tel0207 848 0778
fax0207 848 5408
addressDepartment of Psychological Medicine,
Institute of Psychiatry,
Weston Education Centre,
Cutcombe Rd,
London SE5 9RJ
location 3.11
Weston Education Centre
departmentsCommon Mental and Somatic disorders
Psychological Medicine
alsoGeneral Hospital Psychiatry

biography

Matthew Hotopf is Professor General Hospital Psychiatry. He trained in psychiatry at the Maudsley Hospital, and in epidemiology at the London School of Hygiene and Tropical Medicine. Research interests are in the grey area between medicine and psychiatry, including medically unexplained symptoms; mechanisms of fatigue; depression and anxiety in the context of physical disease; military health; and the assessment of mental capacity. He has an interest in research methodology and evidence based medicine. He is an NIHR Senior Investigator. He works clinically within King’s College Hospital and is visiting psychiatrist to St Christopher’s Hospice.

teaching activities

Undergraduate psychiatry teaching
Post-graduate: evidence based medicine; MScs in Palliative Medicine and Research Methods in Psychiatry; PhD Supervision

RoleCourse
Lecturer
Psychiatric Research » Masters (MSc)

publications



RESEARCH METHODOLOGY
Prince, M. Ford, T. Stewart, R. Hotopf, M (Eds) Practical psychiatric epidemiology Oxford University Press, Oxford (2003) Click here
Hotopf, M. Normand, S. and Lewis, G. The Treatment of Depression: Evaluation and Cost-Effectiveness London School of Hygiene and Tropical Medicine, London (1996) ISSN: 0962-6115
Lewis, G. Churchill, R. Hotopf, M. Systematic Reviews and Meta-Analysis Psychological Medicine (1997) 27: 3-7
Hotopf, M. Wessely, S. and Noah, N. Are Ethical Committees Reliable? Journal of the Royal Society of Medicine (1995) 88 31-33
Hotopf, M. Lewis, G. and Normand, C. Putting trials on trial: the costs and consequences of small clinical trials in depression: a systematic review of methodology Journal of Epidemiology and Community Health (1997) 51 354-358
Hotopf, M. Sharp, D. and Lewis, G. What’s in a Name? A comparison of four psychiatric assessments Social Psychiatry and Psychiatric Epidemiology (1998) 33:27-31
Hotopf, M. The case control study International Review of Psychiatry (1998) 10 278-283
Hotopf, M. Churchill, R. Lewis, G. The pragmatic randomised controlled trial in psychiatry Br J Psychiatry (1999) 175 217-223
Barbui, C. Hotopf, M. Forty years of randomised trials of antidepressants Acta Psychiatrica Scandinavica. 2001; 104: 92-95
Hotopf, M. Pragmatic randomised controlled trials. Advances in Psychiatric Treatment 2002 8: 326-333.
Sumathipala A, Siribaddana S, De Silva N, Fernando D. Abeysingha MRN, Dayaratne,R., Se Silva, D. Warynasuriya,N. Hotopf M. Sri Lankan Twin Registry (2002) Twin Research 5 424-6
Sumathipala A, Siribaddana SH, Abeysingha MRN, De Silva N, Fernando DJS. Dayaratne, DARK, Dr Silva, D. Warnasuriya, ND. Hotopf M. Challenges in Recruiting older Twins for the Sri Lanka Twin Registry. Twin Research 2003 6:67-71
Barbui, C. Hotopf, M. Revisioni e decisioni in psychiatria [systematic reviews and clinical decisions in psychaitry] Epidemiologia e Psichiatria Sociale 2003 12: 154-159
Barbui, C. Percudani, M. Hotopf, M. Economic evaluation of antidepressive agents: a systematic critique of experimental and quasi-experimental studies J Clinical Psychopharmacology 2003 23 145-54
Barbui, C. Cipriani, A. Brambilla, P. Hotopf, M. ‘Wish bias’ in antidepressant drug trials. J Clin Psychopharmacol 2004 34 126-130
Hotopf, M. and Wessely, S. Epidemiology and the fog of war: lessons from the 1990-1991 Gulf War International Journal of Epidemiology 2005; 34; 771-80
Hotopf, M. & Barbui, C. Bias in the evaluation of antidepressants Epidemiologia e Psichiatria Sociale 2005 14 55-57
Wood, A.M. White, I.R. Hotopf, M. Using number of failed contact attempts to adjust for non-ignorable non-response In press: Journal of the Royal Statistical Society, Series A
Cho, H.J. Hotopf, M. Wessely, S. The placebo response in the treatment of chronic fatigue syndrome: a systematic review and meta-analysis Psychosomatic Medicine 2005 67 301-313
Iversen, A. Liddell, K. Fear, N. Hotopf, M. Wessely, S. Consent confidentiality and the Data Protection Act Br Med J 2006 332 165-9
Lee, W. Bindman, J. Ford, T. Glozier, N. Moran, P. Stewart, R. Hotopf, M. Bias in psychiatric case-control studies: A systematic review of current practice Br J Psychiatry 2007, 190 204-209
Stewart, R. Soremekun, M. Perera, G. Broadbent, M. Callard, F. Denis, M. Hotopf, M. Thornicroft, G. Lovestone, S. The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) case register: development and descriptive data BMC Psychiatry 2009, 9:51 doi:10.1186/1471-244X-9-51 Click here

EPIDEMIOLOGY AND AETIOLOGY OF UNEXPLAINED PHYSICAL SYMPTOMS
Hotopf, M. Carr, S. Mayou, R. Wadsworth, M. Wessely, S. Why do children have chronic abdominal pain, and what happens when they grow up? Br Med J (1998) 316:1196-1200
Hotopf, M. Mayou, R. Wadsworth, M. Wessely, S. (1998) Temporal relationships between physical symptoms and psychiatric disorder: results from a national birth cohort Br J Psychiatry 173 255-261
Reid, S. Crayford, T. Nimnuan, T. Richards, S. Hotopf, M. Recognition of Medically Unexplained Symptoms - do doctors agree? (1999) J Psychosom Res 47 483-5
Hotopf, M. Mayou, R. Wadsworth, M. Wessely, S. Childhood risk factors for adult medically unexplained symptoms: results from a national birth cohort study Am. J. Psychiatry (1999) 156; 1796-1800
Hotopf, M. Mayou, R. Wadsworth, M. Wessely, S. Psychosocial and developmental antecedents of chest pain in young adults Psychosomatic Medicine (1999) 61; 861-867
Wessely S. Hotopf M. Is fibromyalgia a distinct clinical entity? Historical and epidemiological evidence. Best Practice & Research in Clinical Rheumatology. 13(3):427-36 (1999)
Nimnuan, C. Hotopf, M. Wessely, S. Medically unexplained symptoms: how often and why are they missed? Quarterly Journal of Medicine (2000) 93: 21-28.
Hotopf, M. Mayou, R. Wadsworth M. Wilson Jones, C. Wessely, S. Childhood predictors of adult medically unexplained hospitalizations. Results from a National Birth Cohort Br J Psychiatry (2000) 176; 273-280
Reid S, Wessely S, Crayford, T, Hotopf M. Medically unexplained symptoms in frequent attenders of secondary health care. British Medical Journal 2001, 322; 767
Fearon, P. Hotopf, M. Relation between headache in childhood and physical and psychiatric symptoms in adulthood: national birth cohort study BMJ 2001;322:1145-1148
Hotopf M, Wadsworth M, Wessely S. Is "somatisation" a defence against the acknowledgement of psychiatric disorder? J Psychosomatic Research 2001: 119-124
Reid S, Whooley D, Crayford T, Hotopf M. Medically unexplained symptoms - GPs’ attitudes towards their cause and management. Family Practice 2001; 18:519-523
Nimnuan, T. Hotopf, M. Wessely, S. Medically unexplained symptoms: an epidemiological study in seven specialities. Journal of Psychosomatic Research 2001;51:361-367.
Nimnuan, C; Rabe-Hesketh, S. Wessely, S. Hotopf, M. How many functional somatic syndromes? Journal of Psychosomatic Research, 2001 51; 549-557
Reid, S. Crayford, T. Patel, A. Wessely, S. Hotopf, M. Frequent attenders with medically
unexplained symptoms: service use and costs in secondary care. British
Journal of Psychiatry, 2002; 180: 248-253
Hotopf, M. Childhood risk factors for medically unexplained symptoms: a review. Scandinavian Journal of Psychology 2002 43 139-146
Reid, S. Crayford, T. Patel, A. Wessely, S Hotopf M. Frequent attenders in secondary care:a 3 year follow-up study of patients with medically unexplained symptoms Psychological Medicine 2003 33 519-524
Goodwin, RD. Hoven, CW. Murison, R. and Hotopf, M. Association Between Childhood Physical Abuse and Gastrointestinal Disorders and Migraine in Adulthood Am J Public Health 2003 93: 1065-1067
Hotopf, M. Preventing somatization Psychological Medicine 2004 34:195-197
Ramchandani, P. Hotopf, M. Stein, A. The epidemiology of recurrent abdominal pain from ages 2 to 6 years: results of a large population based study. Pediatrics 2005 116 46-50

FATIGUE AND CHRONIC FATIGUE SYNDROME
Wessely, S. Hotopf, M. and Sharpe, M. Chronic Fatigue and its Syndromes Oxford University Press, Oxford (1998)Click here
Hotopf, M. Wessely, S. and Noah, N. Chronic fatigue and psychiatric morbidity following viral meningitis Journal of Neurology Neurosurgery and Psychiatry (1996) 60: 504-509
Joyce, J., Hotopf, M. and Wessely, S. Outcome of chronic fatigue and chronic fatigue syndrome Quarterly Journal of Medicine (1997) 90 223-233
Hotopf, M. Wessely S. Chronic fatigue syndrome - mapping the interior Psychological Medicine (1999) 29:255-258.
Reid, S. Chalder, T. Cleare, A. Hotopf, M. Wessely, S. Chronic fatigue syndrome Clinical Evidence (1999) 2:297-405
Reid, S. Chalder, T. Cleare, A. Hotopf, M. Wessely, S. Chronic fatigue syndrome Br Med J 2000; 320: 292-296.
Rubin, G.J. & Hotopf, M. Systematic review and meta-analysis of interventions for post-operative fatigue: British Journal of Surgery 2002 89 971-984
Candy, B. Chalder, T. Cleare, A. Wessely, S. White, P.D. Hotopf, M. Recovery from glandular fever: a case for more than symptomatic therapy? A systematic review British Journal of General Practice 2002 52: 844-851
Candy, B. Chalder, T. Cleare, A. Peakman, M. Skowera, A. Weinman, J. Wessely, S. Zuckerman, M. Hotopf, M. Predictors of fatigue following the onset of infectious mononucleosis. Psychological Medicine 2003 33, 847-855
Chalder, T. Goodman, R. Wessely, S. Hotopf, M. Meltzer, H. Epidemiology of chronic fatigue syndrome and self reported myalgic encephalomyelitis in 5-15 year olds: cross sectional study BMJ, Sep 2003; 327: 654 - 655.
Candy, B. Chalder, T. Cleare, A. Wessely, S. Hotopf, M A randomised controlled trial of a psycho-educational intervention to aid recovery in infectious mononucleosis. Journal of Psychosomatic Research 2004 57; 89-94
Viner, R. Hotopf, M. Childhood predictors of adult self-reported Chronic fatigue syndrome / Myalgic encephalomyelitis (CFS/ME) in a national birth cohort British Medical Journal 2004, 329 941
Rubin, G.J. Hardy, R. Hotopf, M. Incidence and severity of post-operative fatigue: a systematic review and meta-analysis Journal of Psychosomatic Research 2004 57 317-26
Rubin, G.J. Cleare, A. Hotopf, M. Psychosocial factors in post-operative fatigue Psychosomatic Medicine 2004 66: 959-64
Williamson, R.J. Purcell, S. Sterne, A. Wessely, S. Hotopf, M. Farmer, A. Sham P. A Sibling pair analysis of fatigue and its relationship with mental health Social Psychiatry and Psychiatric Epidemiology 2005 40 126-132
Cairns, R. and Hotopf, M. Prognosis of chronic fatigue syndrome: a systematic review Occupational Medicine 2005 55 20-31
Rubin, G. J. Hotopf, M. Papadopoulos, A. Cleare, A. Salivary cortisol as a predictor of post-operative fatigue Psychosomatic Medicine 2005 67: 441-447
Candy, B. Chalder, T. Cleare, A. Wessely, S. Hotopf, M. What advice do General Practitioners give patients with glandular fever? Journal of Psychosomatic Research 2005 58 435-7
Reid S. Chalder T. Cleare A. Hotopf M. Wessely S. Chronic fatigue syndrome. American Family Physician. 2005 72 1793-1-1793-15.
Harvey, S. Wadsworth, MEJ. Wessely, S. Hotopf, M. Etiology of chronic fatigue syndrome: testing popular hypotheses using a national birth cohort study. Psychosomatic Medicine (2008) PSY.0b013e31816a8dbcv1
Harvey SB, Wadsworth M, Wessely S, Hotopf M. The relationship between prior psychiatric disorder and chronic fatigue: evidence from a national birth cohort study. Psychol Med 2008;38:933-40.
Harvey, S.B. Kuh, D. Wessely, S. Hotopf, M. The relationship between fatigue and psychiatric disorders: evidence for the concept of neurasthenia. Journal of Psychosomatic Research 2009;66(5):445-54.

PALLIATIVE CARE AND PHYSICAL DISEASE
Hotopf, M. Chidgey, J. Kelly, L. Addington-Hall, J. Depression in advanced disease – a systematic review: prevalence and case finding. Palliative Medicine 2002 16 81-97
Ly, KL. Chidey, J. Addington-Hall, J. Hotopf, M. Depression in advanced disease – a systematic review: treatment. Palliative Medicine 2002 16 279-84
Henderson, M. Addington-Hall, J. Hotopf, M. The willingness of palliative care patients to participate in research Journal of Pain and Symptom Management 2005 29 116-118 (research letter)
Koffman, J. Donaldson, N. Hotopf, M. Higginson, I.J. Does Ethnicity Matter? Bereavement outcomes in two ethnic groups living in the United Kingdom. Palliative and Supportive Care 2005, 3 183-190
Abas, M.A., Hotopf, M. Prince, M. Depression and mortality in a high-risk population: II-Year follow-up of the Medical Research Council Elderly Hypertension Trial. Br J Psychiatry 181 (2):123-128, 2002.
Maddock, C. Landau, S Barry, K. Maulayah, P. Hotopf, M Cleare, A. Norris, S Pariante CM. Psychopathological symptoms during interferon-a and ribavirin treatment: effects on virologic respsonse Molecular Psychiatry 2005 10 332-333
Henderson, M. Safa, F. Easterbrook, P. Hotopf, M. Fatigue in HIV in the era of highly active antiretroviral therapy HIV Medicine 2005 6 347-352
Armes, J. Chalder, T. Addington-Hall, J. Richardson A. Hotopf, M A randomised controlled trial to evaluate the effectiveness of a brief behaviourally oriented intervention for cancer-related fatigue Cancer (2007) 110 1385-1395
Minton, O. Richardson, A. Sharpe, M. Hotopf, M. Stone, P. A systematic review and meta-analysis of the pharmacological treatment of cancer-related fatigue (CRF) Journal of the National Cancer Institute (2008) 100 1155-1166
Moorey, S. Cort, E. Kapari, M. Monroe, B. Hansford, P. Mannix, K. Henderson, M. Fisher, L. Hotopf, M. A cluster randomized controlled trial of cognitive behaviour therapy for common mental disorders in patients with advanced cancer Psychological Medicine 2008 doi: 10.1017/s0033291708004169
Price, A. Hotopf, M. The treatment of depression in patients with advanced cancer undergoing palliative care Current Opinions in Supportive and Palliative Care 2009 3 61-66
Lee, W.E. Price, A. Rayner, L. Hotopf, M. Survey of doctors’ opinions of the legalisation of physician assisted suicide. BMC Medical Ethics 2009 10: 2
Shipman, C. Hotopf, M. Richardson, A. Murray, S. Koffman, J. Harding, R. Higginson, I.J. The views of patients with advanced cancer regarding participation in serial interview studies Palliative Medicine 2008 22(8):913-20


SYSTEMATIC REVIEWS AND OTHER STUDIES ON TREATMENTS
Hotopf, M. Lewis, G. and Normand, C. Are SSRIs a cost-effective alternative to tricyclics? British Journal of Psychiatry (1996) 168: 404-409
Hotopf, M. Hardy, R. & Lewis, G. Discontinuation Rates of SSRIs and Tricyclic Antidepressants: A Meta-Analysis and Investigation of Heterogeneity British Journal of Psychiatry (1997) 170: 120-127
Lima, M.S. & Hotopf, M.H. Drugs for Dysthymia [Protocol]. In: Oakley-Browne M, Bech P, Churchill R, Gill D, Hazell P, Trivedi M, Wessely S (eds). Depression, Anxiety and Neurosis Module of The Cochrane Database of Systematic Reviews, [updated July 1997]. Available in The Cochrane Library [database on disk and CDROM]. The Cochrane Collaboration; Issue 3. Oxford: Update Software; 1997. Updated quarterly.
Lima, M. S. Hotopf, M. Wessely, S. The efficacy of drug treatments for dysthymia: a systematic review and meta-analysis Psychological Medicine (1999) 29; 1273-1289
Lima, M.S. Hotopf, M. Mari, J.J. Béria, J.U. de Bastos, A.B. Mann, A. Psychiatric disorder and the use of benzodiazepines: an example of the inverse care law from Brazil Social Psychiatry Psychiatric Epidemiology (1999) 34: 316-322
Barbui C, Hotopf M, Freemantle N, Boynton J, Churchill R, Eccles MP, Geddes JR, Hardy R, Lewis G, Mason JM. Selective serotonin reuptake inhibitors versus tricyclic and heterocyclic antidepressants: comparison of drug adherence (Cochrane Review). In: The Cochrane Library, Issue 4, 2000. Oxford: Update Software.
Barbui, C. & Hotopf, M. Amitriptyline vs the rest: still the leading antidepressant after 40 years of randomised controlled trials. British Journal of Psychiatry 2001 178 129-144
Barbui, C. Hotopf, M. Garattini, S. Fluoxetine dose and outcome in antidepressant drug trials European Journal of Clinical Pharmacology 2002 58: 379-386
Lima, M. Hotopf, M. Benefits and risks of pharmacotherapy for dysthymia: a systematic appraisal of the evidence. Drug Safety 2003 26: 55-64
Guaiana G. Barbui C. Hotopf M. Amitriptyline versus other types of pharmacotherapy for depression (Cochrane Review). Cochrane Database of Systematic Reviews. (2):CD004186, 2003.
Silva de Lima M. Hotopf M. A comparison of active drugs for the treatment of dysthymia. Cochrane Database of Systematic Reviews. (3):CD004047, 2003.
Barbui C , Guaiana G, Hotopf M. Amitriptyline for inpatients and SSRIs for outpatients with depression? Systematic review and meta-regression analysis. Pharmacopsychiatry 2004, 37, 93-97
De Lima, M. Mari, J.J. Breier, A. Costa, A.M. de Sena, E.P. Hotopf, M. Quality of life in schizophrenia: a multicenter, randomized, naturalistic, controlled trial comparing olanzapine to first-generation antipsychotics Journal of Clinical Psychiatry 2005; 66; 831-8
Minton, O. Richardson, A. Sharpe, M. Hotopf, M. Stone, P. A systematic review and meta-analysis of the pharmacological treatment of cancer-related fatigue (CRF) Journal of the National Cancer Institute (2008) 100 1155-1166


MILITARY HEALTH
Unwin, C. Blatchley, N. Coker, W. Ferry, S. Hotopf, M. Hull, L. Ismail, K. Palmer, I. David, A. Wessely, S. The health of United Kingdom servicemen who served in the Persian Gulf War. Lancet (1999) 353 169-178
Hotopf, M. David, A. Hull, L. Ismail, K. Unwin, C. Wessely, S. The role of vaccinations as risk factors for ill health in veterans of the Persian Gulf War
Br. Med J (2000) 320; 1363-7
Ismail, K. Blatchley, N. Hotopf, M. Hull, L. Palmer, I. Unwin, C. David, A. Wessely, S. Occupational risk factors for ill health in Gulf War veterans of the United Kingdom J Epidemiology and Community Health 2000; 54: 834-8
Reid S, Hotopf M, Hull L, Ismail K, Unwin C, David A, Wessely S. Chronic fatigue syndrome and multiple chemical sensitivity in UK Gulf war veterans. American Journal of Epidemiology 2001 153 604-9
Chalder T, Hotopf M, Unwin C, David A, Hull L, Wessely S. Prevalence of Gulf War Veterans who believe they have Gulf War Syndrome: A questionnaire study British Medical Journal 2001; 323 473-6
Reid, S. Hotopf, M. Hull, L. Ismail, K. Unwin, C. Wessely, S. Reported chemical sensitivities in a health survey of UK military personnel Occupational and Environmental Medicine 2002;59:196-8
Unwin C, Hotopf M, David A, Hull L, Ismail K, Wessely S. Women in the Persian Gulf: lack of gender differences in long term health effects of service in UK armed forces in the 1991 Persian Gulf War Military Medicine 2002 167; 406-413
Ismail K, Kent K, Brugha T, Hotopf M, Hull L, Seed P, Palmer I, Reid S, Unwin C, David A, Wessely S. The mental health of UK Gulf war veterans: phase 2 of a two-phase cohort study. Br Med J 2002: 325:576-579
Hull, L. David, A. Hyams, K.C. Unwin, C. Wessely, S. Hotopf, M. Self-reported health of Persian Gulf War veterans: A comparison of help-seeking and randomly ascertained cases. Military Medicine 2002 9 747-752
Hotopf, M. David, A. Hull, L, Ismail I. Palmer, I. Unwin, C. Wessely, S. The health effects of peace-keeping in the UK Armed Forces: Bosnia 1992-1996. Predictors of psychological symptoms. Psychological Medicine 2003: 33:155-162
Hotopf, M Treating Gulf War Veterans’ illnesses: are more focussed studies needed? Journal of the American Medical Association 2003 289 1436-7
Hotopf, M. David, A. Hull, L. Ismail, I. Unwin, C. Wessely, S. The health effects of peace-keeping in the UK armed forces: Bosnia 1992-1996. A cross sectional study: comparison with non-deployed military personnel. Military Medicine 2003: 168: 408-413
Hotopf, M. Mackness, M.I. Nikolaou, V. Collier, D. David, A. Durrington, P.N. Hull, L. Ismail, K Peakman, M. Unwin,C. Wessely, S. Mackness, B. Paraoxonase in Persian Gulf War Veterans Journal of Occupational and Environmental Medicine 2003; 45, 668-675
Wessely, S. Unwin, C. Hotopf, M. Ismail, K. Nikolaou, V. David, A. The stability of recall of military hazards over time: Evidence from the Gulf War Br J Psychiatry 2003; 183: 314 - 322.
Hotopf, M. David, A. Hull, L. Nikalaou, V. Unwin, C. Wessely, S. Gulf War illness – better, worse or just the same? A cohort study Br. Med J. 2003;327:1370,
Macfarlane GJ, Biggs, AM. Maconachie N. Doyle, P. Hotopf, M Lunt, M. Cancer incidence amongst United Kingdom Gulf war veterans Br Med J 2003;327:1373
Iversen, A. Nikolaou, V. Greenberg, N. Unwin, C. Hull, L. Hotopf, M. Dandeker, C. Ross, J. Wessely, S. What happens to British veterans when they leave the armed forces? European Journal of Public Health 2005 15: 175-184
Iversen A, Dyson C, Smith N, Greenberg N, Walwyn, R, Unwin C, Hull L, Hotopf M, Dandeker C, Ross J, Wessely S ‘Goodbye and Good luck’; the mental health needs and treatment experiences of British Veterans Br J Psychiatry 2005 186 480-6
Macfarlane, G.J. Hotopf, M. Maconochie, N. Blatchley, N. Richards, A. and Lunt, M. Long-term mortality amongst Gulf War veterans: is there a relationship with experiences during deployment and subsequent morbidity? Int J Epidemiol 2005 34 1403-1408
Peakman, M. Skowera, A. Hotopf, M. Immunological dysfunction, vaccination, and Gulf War illness Philosophical Transactions Royal Society B 2006, 361 681-7
Murphy, D. Dandeker, C. Horn, O. Hotopf, M. Hull, L. Jones, M. Marteau, T. Rona, R. Wessely, S. UK Armed Force’s responses to an informed consent policy for anthrax vaccination: a paradoxical effect? Vaccine 2006 3109-3114
Wessely S. and Hotopf, M. Something old, something new, something borrowed, something blue: the story of “Gulf War Syndrome” In Medical and psychiatric comorbidity over the course of life W.W. Eaton (Ed) American Psychaitric Publishing, Washington DC (2005)
Wessely S, Chalder T, David A, Hotopf M, Ismail L, Jones E, Palmer I, Reid S, Unwin C. Ten Years On: What Do We Know About Gulf War Syndrome? In: Toxic Turmoil: Psychological and Societal Consequences of Ecological Disasters (ed Havenaar. Cwikel, Bromet), Plenum 2002: 101-128
Hotopf, M. Hull, L. Fear, NT, Browne, T. Horn, O. Iversen, A. Jones, M. Murphy, D. Bland, D. Earnshaw, M. Greenberg, N. Hacker Hughes, J. Tate, AR. Dandeker, C. Rona, R. Wessely, S. The health of UK military personnel who deployed to the 2003 Iraq War Lancet 2006: 367: 1731-1741
Horn, O, Hull, L. Jones, M. Murphy, D. Browne, T. Fear, NT, Hotopf, M. Rona, RJ. Wessely, S. Is there an ‘Iraq War Syndrome’? Lancet 2006: 367: 1742-1746.
Browne, T. Hull, L. Horn, O. Jones, M. Murphy, D. Fear, N. Greenberg, N. French, C. Rona, R. Wessely, S. Hotopf, M. Explanations for the increase in mental health problems in UK Reserve Forces who have served in Iraq Br J Psychiatry 2007 190 484 489 Click here
Rona, R.R. Fear, N. T. Hull, L Greenberg, N. Earnshaw, M. Hotopf, M. Wessely, S. The mental health consequences of “over-stretch” in the UK Armed Forces British Medical Journal (2007) 335 603-7
Iversen, A.C. Fear, N.T. Ehlers, A. Hacker Hughes, J. Hull, N. Earnshaw, M. Greenberg, N. Rona, R. Wessely, S. Hotopf, M. Risk factors for post traumatic stress disorder amongst United Kingdom Armed Forces personnel Psychological Medicine 2008 38 511-522
Browne, T. Iversen, A. Hull, L Workman, L. Barker, C. Horn, O. Jones, M. Murphy, D. Greenberg, N. Rona, R. Hotopf, M. Wessely, S. Fear, N.T. How do experiences in Iraq affect alcohol use in male UK armed forces personnel? Occupational and Environmental Medicine (2008) 65 628-33
Murphy, D. Marteau, T. Rona, R. Hotopf, M. Wessely, S Why do UK military personnel refuse the anthrax vaccination? Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science 2008, 6: 237-242.
Fear, N.T. Iversen, A. Meltzer, H. Workman, L. Hull, L. Greenberg, N. Barker, C. Browne, T. Earnshaw, M. Horn, O. Jones, M. Murphy, D. Rona, R. Hotopf, M. Wessely, S. Patterns of drinking in the UK Armed Forces Addiction (2007). 102 1749-59
Rona, R. Fear, N. Iversen, A. Jones, M. Hull, L. Greenberg, N. Hotopf, M. Wessely S. The impact of post traumatic stress disorder on impairment in the UK military at the time of the Iraq war J. Psychiatric Research (2008) doi: 10.1016/j.jpsychires.2008.09.006
Rona, R.J. Hooper, R. Jones, M. Iversen, A.C. Hull, L. Murphy, D. Hotopf, M. Wessely, S. The contribution of prior psychological symptoms and combat exposure to post Iraq deployment mental health in the UK Military J Traumatic Stress 2009 22 11-19



MENTAL CAPACITY AND MENTAL HEALTH LEGISLATION
Wall, S. Buchanan, A. Fahy, T. Hotopf, M. Wessely, S. Churchill, R. A systematic review into the use of the Mental Health Act, 1983 Department of Health, London (1999)
Wall, S. Hotopf, M. Wessely, S. Churchill, R. Trends in the use of the Mental: England, 1984-96. Br Med Journal (1999) 318: 1520-1521
Hotopf, M. Wall, S. Buchanan, A. Wessely, S. Churchill R Changing patterns in the use of the Mental Health Act (1983) in England from 1984-1996 Br J Psychiatry (2000) 176; 479-484
Shaw, P. Davies, A. Hotopf, M. In relative danger? The outcome of patients discharged by their nearest relative from Sections 2 and 3 of the Mental Health Act Psychiatric Bulletin 2003, 27 50-54
Skowera, A. Hotopf,M. Sawicka, E. Varela-Calvino, R. Unwin, C. Nikolau,V. Hull, L. Ismail, K. David, A.. Wessely, S. Peakman, M. T helper 2 type immune activation in Gulf War veterans with multi-symptom illness Journal of Clinical Immunology 2004 24 66-73
Hotopf, M. David, A. Hull, L. Nikalaou, V. Unwin, C. Wessely, S. Risk factors for continued illness among Gulf War veterans: a cohort study. Psychological Medicine 2004 34: 747-754
Raymont, V. Bingley, W. Buchanan, A. David, A. Hayward, P. Wessely, S. Hotopf, M. The Prevalence and Associations of Mental Incapacity in Medical In-Patients Lancet 2004 364: 1421-27
Ranjith, G. Hotopf, M. “Refusing treatment – please see”: an analysis of capacity assessments carried out by a liaison psychiatric service Journal of the Royal Society of Medicine 2004 97 480-82
Cairns, R. Maddock, C. Buchanan, A. David, A.S. Hayward, P. Richardson, G. Szmukler, G. Hotopf, M. Assessment of mental capacity in individuals with mental illness: an inter-rater reliability study. Br J Psychiatry 2005 187 372-378
Cairns, R. Maddock, C. Buchanan, A. David, A.S. Hayward, P. Richardson, G. Szmukler, G. Hotopf, M. Prevalence and predictors of mental incapacity in psychiatric in-patients. Br. J. Psychiatry 2005 187 379-85
Hotopf, M. The assessment of mental capacity Clinical Medicine, 2005 5 580-584
Hotopf, M. Mental capacity and empirical research Journal of Mental Health 2006 15: 1-6
Raymont, V. Bingley, W. Buchanan, A. David, A. Hayward, P. Wessely, S. Hotopf, M. Assessing the Inter-rater Reliability of Assessments of Mental Capacity International Journal of Law and Psychiatry (2007) 30 112-117
Olumoroti, O.J., Kassim, A. Hotopf, M. The impact of contexts on the assessment of mental capacity by psychiatrists Journal of Mental Health (2007) 16: 521-8
Okai, D. A. Owen, G.S. McGuire, H. Singh, S.P. Churchill, R. Hotopf, M. Mental Capacity in Psychiatric Patients: A Systematic review Br J Psychiatry (2007) 191 291-297
Nicholson, T. Cutter, W. Hotopf, M. Assessing Mental Capacity: The Mental Capacity Act (2008) Br. Med. J. 336 322-325
Owen, G.S. Freyehagen, F. Hayward, P. Richardson, G. Hotopf, M. Mental Capacity and Judgmental Autonomy: An Interdisciplinary Challenge. Inquiry 2009 52 79-107
Hotopf, M. Laird, B. Singh, I. Churchill, R. David, A.S. McLoughlin, D.M. Richardson, G. Szmukler, G. Capacity, consent and electroconvulsive therapy: a qualitative and cross-sectional study J Mental Health (2008) 17 315-25
Owen, G.S. Richardson, G. David, A.S. Szmukler, G. Hayward, P. Hotopf, M. Mental capacity to make treatment decisions in patients admitted to a psychiatric hospital – cross sectional study. Br Med J 337 (301): a448. (2008)
Owen, G.S. Richardson, G. David, A.S. Szmukler, G. Hayward, P. Hotopf, M. Mental capacity, diagnosis, and insight in psychiatric inpatients: a cross sectional study Psychological Medicine 2009 39 1389-98
Owen, G.S. Szmukler, S. Richardson, G. David, A.S. Hayward, P. Rucker, J. Harding, D. Hotopf, M. Mental capacity and psychiatric inpatients: some implications for the new mental health law. Br J Psychiatry 2009 195: 257-263


OTHER
Hotopf, M. & Wessely, S. Stress in the workplace: unfinished business Journal of Psychosomatic Research (1997) 43 1-6
Hotopf, M. Unexplained physical symptoms in the workplace Advances in Psychiatric Treatment (1998) 4:151-8
Wessely S, Hotopf M. Are some public-health problems better neglected? Lancet 2001: 357:976-978.
Henderson, M. Holland Elliott, K. Wessely S Hotopf M Liaison Psychiatry and Occupational Health Occupational Health 2001 51 479-481
Henderson, M. Hotopf, M. Wessely, S. Workplace counselling: an appeal for evidence Occupational and Environmental Medicine2003 60 899-900
Lee, W. Hotopf, M Personality variation with age: Trait instability or measurement unreliability? Personality and Individual Differences 2005 vol 38, 883-890
Lee, W. Wadsworth M.E.J. Hotopf, M The protective role of trait anxiety Psychological Medicine 2006 36 345-51
Øverland, S. Glozier, N Henderson, M. Mæland J.G. Hotopf, M Mykletun, A. Health status before, during and after disability pension award: The Hordaland Health Study (HUSK) Journal of Occupational and Environmental Medicine 2008 65 769-73
Henderson, M. Hotopf, M. Leon, D. Childhood temperament predicts long term sickness absence – evidence from the Aberdeen Children of the 1950s Cohort Study Br J Psychiatry 2009 194 220-223
Harvey, S. Henderson, M. Lelliott, P. Hotopf, M. Much work still to be done - mental health and employment Br J Psychiatry 2009 194 201-3






last updated: Thursday, October 01, 2009