Dr James H MacCabe  BSc MBBS MRCPsych MSc PhD
Senior lecturer
Honorary Consultant Psychiatrist, National Psychosis Unit
Head, Maudsley Debates

biography

After an intercalated BSc in Psychology and Basic Medical Sciences, Dr MacCabe qualified in medicine at the University of London in 1995 and completed his basic and higher specialist training in Psychiatry at the Maudsley Hospital from 1997 to 2004. He obtained a joint MRC/Department of Health Special Training Fellowship in Health of the population research in 2004, in collaboration with the Department of Medical Epidemiology and Biostatistics at Karolinska Institute, Stockholm. He obtained an MSc in Epidemiology from the London School of Hygiene and Tropical Medicine in 2006 and a PhD in 2008. In 2009 he was awarded a Clinical Senior Lectureship by the Higher Education Funding Council for England.

Dr MacCabe conducts research into the causes and consequences of psychoses using the tools of lifecourse epidemiology. Much of his research is conducted in collaboration with international partners in Sweden and elsewhere.

Dr MacCabe has been honorary consultant psychiatrist at the National Psychosis Unit since 2005, where he is responsible for treating inpatients with severe psychosis and conducting clinical trials.

Dr MacCabe is special advisor on psychosis to the mental health charity, SANE.

teaching activities

Maudsley Forum

Tutor

Advanced Maudsley Forum

Tutor

publications

JOURNAL PUBLICATIONS

RESEARCHER ID at www.researcherid.com = E-5210-2010

Bundy H, Stahl D, MacCabe JH. (2010) A systematic review and meta-analysis of the fertility of patients with schizophrenia and their unaffected relatives. Acta Psychiatrica Scandinavica IN PRESS

Crews MP, Dhillon GS, MacCabe JH. (2010) Clozapine rechallenge following clozapine-induced pericarditis. J Clin Psychiatry. 2010 Jul;71(7):959-61.

MacCabe, JH. Lambe, M., Cnattingius S, Sham PC, David AS, Reichenberg A, Murray RM, Hultman CM. (2010) Excellent school performance at age 16 increases risk of adult bipolar disorder: a national cohort study. Br J Psychiatry. 2010 Feb;196(2):109-15

MacCabe JH, Koupil I, Leon DA. (2009) Reproductive success in patients with psychosis and their unaffected siblings: a study of fertility over two generations in a cohort born 1915-1929 in Uppsala, Sweden. Psychol Med. 2009 Oct;39(10):1667-76

Reichenberg A, Mill J, MacCabe JH. (2009) Epigenetics, Genomic Mutations and Cognitive Function. Cogn Neuropsychiatry. 2009;14(4-5):377-90.

Zanelli, J. MacCabe JH. Toulopoulou T, Rabe-Hesketh S, Walshe M, McDonald CD Murray RM. (2008) Neuropsychological correlates of eye movement abnormalities in schizophrenic patients and their unaffected relatives. J Psychiatry Research Res. 2009 Aug 15;168(3):193-7

MacCabe JH. (2008) Population-based Cohort Studies on Premorbid Cognitive Function in Schizophrenia. Epidemiologic Reviews 2008; doi: 10.1093/epirev/mxn007

Peters, ER, Thornton P, Siksou L., Linney Y., MacCabe, JH. (2008) Specificity and origins of the Jump to conclusion” bias in deluded patients. Brit Jnl Clinical Psychology 47: 239-244

MacCabe JH, Lambe MP, Cnattingius S, Torrång A, Björk C, Sham PC, David AS, Murray RM, Hultman CM. (2008) Scholastic achievement at age 16 and risk of schizophrenia and other non-affective psychoses: a national cohort study. Psychol Med 38(8): 1133-1140

Reichenberg A, MacCabe JH. (2007) Feeling the pressure: work stress and mental health (Editorial). Psychol Med 31; 1-2

MacCabe JH, Martinsson L, Lichtenstein P, Nilsson E, Cnattingius S, Murray RM, Hultman C. (2007) Adverse pregnancy outcomes in mothers with affective psychosis. Bipolar Disorders 9(3): 305-309

MacCabe JH, Sunbaunat K, Bunthoeun P. (2007) Psychiatry in Cambodia: the phoenix rises from the ashes. International Psychiatry 4(2): 37-38

MacCabe, JH. (2006) Good financial management does not necessarily lead to better services (letter). BMJ. Oct 28;333(7574):920

Lambe M, Hultman C, Torrang A, MacCabe JH, Cnattingius S. (2006) Maternal Smoking During Pregnancy and School Performance at Age 15. Epidemiology 17(5): 524-530.

Bramon E, Dempster E, Frangou S, McDonald C, Schoenberg P, MacCabe JH, Walshe M, Sham P, Collier D, Murray RM. (2006) Is there an association between the COMT gene and P300 endophenotypes? Eur Psychiatry. Jan;21(1):70-3.

Schulze K, MacCabe JH, Rabe-Hesketh S, Crawford T, Marshall N, Zanelli J, Walshe M, Bramon E, Murray RM, McDonald C. (2006). The relationship between eye movement and brain structural abnormalities in patients with schizophrenia and their unaffected relatives. J Psychiatr Res.40: 589-598

MacCabe JH, Simon H, Zanelli JW, Walwyn R, McDonald CD, Murray RM. Saccadic distractibility is elevated in schizophrenia patients, but not in their unaffected relatives. Psychol Med. 2005

Zanelli JW, Simon H, Rabe-Hesketh S, Walshe M, McDonald CD, Murray RM, MacCabe JH. (2005) Eye tracking in schizophrenia: does the antisaccade task measure anything that the smooth pursuit task does not? Psychiatry Research 136, 181-188

McDonald CD, Bullmore ET, Sham PC, Chitnis X, Suckling J, MacCabe JH, Walshe M, Murray RM. (2005) Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: a computational morphometry study. Br J Psychiatry 186: 369-377

MacCabe, JH, Travis, M. Clozapine-induced obsessive-compulsive symptoms (letter). (2004) Progress in Neuro-psychopharmacology and biological psychiatry, Progress in Neuropsychopharmacology and Biological Psychiatry 28 (2004) 1209

MacCabe, JH., Murray, RM. (2004) Intellectual functioning in schizophrenia: a marker of neurodevelopmental damage? Journal of Intellectual Disability Research 48(6): 519-523

MacCabe, J.H., Aldouri, E., Fahy, T.A., Sham, P.C., Murray, R.M. (2002) Do schizophrenic patients who managed to get to university have a non-neurodevelopmental form of illness? Psychological Medicine, 32: 535–544.

MacCabe, J.H., Marks, I.M., Murray, R.M. (2002) Successful exposure treatment of Clozapine-induced Obsessions and Compulsions: Case Report. (Letter) J Clin Psychiatry 63 (12): 1179 - 1180





BOOKS
MacCabe JH. The extremes of the Bell Curve: Excellent or poor school performance and risk for severe mental disorders. London: Psychology Press, 2010.

MacCabe JH, O’Daly O, Wright P, McGuffin P, Murray RM. (Eds) Beyond Nature Versus Nurture: Genes, environment and their interaction in Psychiatry. Oxford: Taylor And Francis 2006. (Commended, Mental Health category, BMA Book competition 2007)



BOOK CHAPTERS AND MISCELLANEOUS PUBLICATIONS

Hurlow, J, MacCabe, JH. (2009) Paradoxes in creativity and Psychiatric conditions. In: Kapur N, Pascual-Leone A, Ramachandran V (Eds)The Paradoxical Brain. Cambridge: Cambridge University Press. IN PRESS

MacCabe, JH, Zanelli, J. (2006) Are eye tracking abnormalities related to susceptibility genes for schizophrenia? In: McDonald, CD, Murray, RM (Eds.) What is Inherited in Schizophrenia and Bipolar Disorder? – The Maudsley Family Study of Psychosis. London: Psychology Press

MacCabe, JH. (2005) prescribing in pregnancy and breast feeding, In Murray, RM. Goldberg DP. (Eds.) Maudsley Handbook of Practical Psychiatry, 45h edition, Oxford University Press, 2005

Baddeley A, Morris R, David AS, MacCabe JH. (2005) An ABC introduction to cognition for schizophrenia clinicians. In: Morgan K, Eadbard, J, Murray R. (Eds) Cognition and Schizophrenia: Improving Real Life Function

MacCabe, JH. (2003) Intelligence and Schizophrenia (Commissioned article). National Association of Primary Care Review, 3(2): 218-220

MacCabe, JH. (2002) When to refer to Experts, In: Murray, RM. Goldberg DP. (Eds.) Maudsley Handbook of Practical Psychiatry, 4th edition, Oxford University Press, 2002. ISBN 0-19-851609-6

MacCabe JH. (2000). The Latest Drug Treatments for Schizophrenia. In: The Medical Book, 2000. London: Medilink Press.