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Dr Paola Dazzan  MSc PhD MRCPsych
Senior lecturer
Honorary Consultant Psychiatrist
Coordinator Year 3 MBBS Psychiatry Teaching, King's College London School of Medicine

emailcontact this person
tel0207 848 0590
fax0207 701 9044
address

Institute of Psychiatry
Box  P063
De Crespigny Park
London
United Kingdom, SE5 8AF

location M7.08.01
Psychosis Centre
departmentsPsychological Medicine
Psychosis Studies
alsoGeneral Psychiatry

biography

My main area of interest is the application of brain imaging to the study of the early stages of psychosis, and the relationship between brain, other biological risk factors for psychosis, and the biological effects of antipsychotics. I am using different imaging techniques such as structural and functional imaging, and diffusion tensor imaging to explore the role of the neurological abnormalities in schizophrenia, and the presence of brain changes and their progression in psychosis. I am also currently using multimodal imaging longitudinally to establish neuroimaging biomarkers that can be used as predictors of treatment response to antipsychotic drugs in patients at the first episode of a psychosis.

teaching activities

Coordinator of Year 3 Psychiatry Teaching for King’s College London School of Medicine.

Committee Member of the “Maudsley Forum", courses for European Psychiatrists.

PhD Supervisor (please contact Paola Dazzan directly)

RoleCourse
Lecturer
Mental Health Studies » Masters (MSc)
Lecturer
Psychiatric Research » Masters (MSc)

publications

Data-based articles in peer-reviewed journals:

P. Dazzan, T. Lloyd, J. Zanelli, K. Morgan, K. Orr, C. Morgan, P. Fearon, G. Hutchinson, J. Holloway, J. Leff, G. Harrison, P.B. Jones, R. Murray (2008). Neurological soft signs and cognitive ability in first episode psychosis. British Journal of Psychiatry, 193: 197-202.

V. Mondelli, P. Dazzan, A. Gabilondo, K. Tournikioti, M. Walshe, N. Marshall, K.K. Schulze, R.M. Murray, C. McDonald, C.M. Pariante (2008). Pituitary volume in unaffected relatives of patients with schizophrenia and bipolar disorder. Psychoneuroendocrinology, 33: 1004-1012.
H. Fisher, C. Morgan, P. Dazzan, T.K. Craig, K. Morgan, G. Hutchinson, P.B. Jones, G.A. Doody, C. Pariante, P. McGuffin, R.M. Murray, J. Leff, P. Fearon (2008) Gender differences in the association between childhood abuse and psychosis. British Journal of Psychiatry, in press.

U.A. Reininghaus, C. Morgan, J. Simpson, P. Dazzan, K. Morgan, G.A. Doody, D. Bhugra, J. Leff, P. Jones, R.M. Murray, P. Fearon, T.K.Craig (2008). Unemployment, social isolation, achievement-expectation mismatch and psychosis: findings from the AESOP Study. Social Psychiatry Psychiatric Epidemiology, 43: 743-751.
K. Ihara, C. Morgan, P. Fearon, P. Dazzan, A. Demjaha, T. Lloyd, J. Kirkbride, H. Hayhurst, R.M. Murray, P.B. Jones (2008). The Prevalence, Diagnostic Significance and Demographic Characteristics of Schneiderian First Rank Symptoms in an Epidemiological Sample of First Episode Psychoses. Psychopathology, In press.

C. Cooper, C. Morgan, M. Byrne, P. Dazzan, K. Morgan, G. Hutchinson, G.A. Doody, G. Harrison, J. Leff, P. Jones, K. Ismail, R. Murray, P. Bebbington, P. Fearon (2008). Perceptions of disadvantage, ethnicity and psychosis. British Journal of Psychiatry, 192:185-90.
S. Harvey, K. Dean, C. Morgan, E. Walsh, A. Demjaha, P. Dazzan, K. Morgan, T. Lloyd, P. Fearon, P.B. Jones, R.M. Murray (2008). Self-harm in first-episode psychosis. British Journal of Psychiatry, 192:178-184.
A.A. Gibbs, P. Dazzan, K.D. Morgan, K. Naudts, C. Morgan, G. Hutchinson, P. Fearon, J. Leff, R.M. Murray, A. David (2007). Sexually dimorphic changes in the amygdala in relation to delusional beliefs in first episode psychosis. Journal of Psychiatric Research Dec 22; [Epub ahead of print].

S.J. Borgwardt, P.K. McGuire, J. Aston, G. Berger, P. Dazzan, U. Gschwandtner, M. Pflüger, M. D’Souza, E.W. Radue, A. Riecher-Rössler (2007). Structural brain abnormalities in individuals with an at-risk mental state who later develop psychosis. British Journal of Psychiatry Suppl 51:s69-75.
J.B. Kirkbride, J. Boydell, G.B. Ploubidis, C. Morgan, P. Dazzan, K. McKenzie, R.M. Murray, P.B. Jones (2007). Testing the association between the incidence of schizophrenia and social capital in an urban area. Psychological Medicine, 8:1-12.
K.D. Morgan, P. Dazzan, K. Orr, G. Hutchinson, X. Chitnis, J. Suckling, D. Lythgoe, S. Pollock, B. Chapple, S. Rossell, J. Shapleske, A. David, P.K. McGuire, P.B. Jones, J. Leff, R.M. Murray (2006). Structural Brain Abnormalities in First Episode Schizophrenia and Affective Psychosis: The ÆSOP Study. British Journal of Psychiatry Suppl. 51:s111-116.

J.M. Lappin, P. Dazzan*, K.D. Morgan, C. Morgan, G. Hutchinson, X. Chitnis, J. Suckling, P. Fearon, P.B. Jones, J. Leff, R.M. Murray, P.K. McGuire (2007). Duration of prodromal phase predicts severity of volumetric abnormalities in first episode psychosis. British Journal of Psychiatry Suppl. 51s:123-127. *Corresponding author.

J.M. Lappin, K.D. Morgan, C. Morgan, P. Dazzan, et al. (2007). Duration of untreated psychosis and neuropsychological function in first episode psychosis. Schizophrenia Research PMID: 17644343.

J.B. Kirkbride, P. Fearon, C. Morgan, P. Dazzan, R.M. Murray, P.B. Jones (2007) Neighbourhood-level effects on psychoses: re-examining the role of context. Psychological Medicine May 2; 1-13.

J.B. Kirkbride, P. Fearon, C. Morgan, P. Dazzan, K. Morgan, R.M. Murray, P.B. Jones (2007) Neighbourhood variation in the incidence of psychotic disorders in Southeast London.
Social Psychiatry Psychiatric Epidemiology 30; 438-4530.

T. Lloyd, P. Dazzan, K. Dean, P. Fearon, G. Doody, J. Tarrant, K.D. Morgan, C. Morgan, R. Mallett, J. Leff, G. Harrison, R.M. Murray, P.B. Jones (2007). Minor Physical Anomalies in patients with first episode psychosis: theirfrequency and diagnostic specificity. Psychological Medicine, 30; 1-8.

S. Tosato, M. Ruggeri, C. Bonetto, M.E. Bertani, G. Marrella, A. Lasalvia, D. Cristofalo, G. Aprili, M. Tansella, P. Dazzan, M. DiForti, R.M. Murray, D.A. Collier (2007). Association of dysbindin gene with clinical and outcome measures in a representative cohort of Italian schizophrenic patients. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 8; 647-59.

K. Dean, P. Dazzan, T. Lloyd, K. Morgan, G. Hutchinson, K. Orr, P.B. Jones, R.M. Murray, P. Fearon (2006). Minor Physical Anomalies amongst different ethnic groups in a first episode psychosis sample. Schizophrenia Research, 86-90.

P. Dazzan, K. Morgan, K. Orr, G. Hutchinson, X. Chitnis, J. Suckling, P. Fearon, J. Salvo, P.K. McGuire, R.M. Mallett, P.B. Jones, J. Leff, R.M. Murray (2006). Neurological soft signs and their anatomical correlates in healthy individuals. Cerebral Cortex 16, 1225-1231.

J.M. Lappin, K.D. Morgan, C. Morgan, G. Hutchinson, X. Chitnis, J. Suckling, P. Fearon, P.K. McGuire, R.M. Mallett, P.B. Jones, J. Leff, R.M. Murray, P. Dazzan (2006). Grey and White Matter Changes Associated with Duration of Untreated Illness: the AESOP First Episode Psychosis study. Schizophrenia Research 83, 145-153.

K. Dean, P. Fearon, K. Morgan, G. Hutchinson, K. Orr, X. Chitnis, J. Suckling, R. Mallet, J. Leff, P.B. Jones, R.M. Murray, P. Dazzan (2006). Grey matter correlates of minor physical anomalies in the AESOP first episode psychosis study. British Journal of Psychiatry 189, 221-228.

C. Morgan, J. Leff, G. Hutchinson, J. Kirkbride, K. McKenzie, K. Morgan, P. Dazzan, T. Craig, G. Doody, P. Jones, R. Murray, P. Fearon (2006). Parental separation, loss and psychosis in different ethnic groups. A Case-Control Study. Psychological Medicine, 37, 495-503.

S.J. Borgwardt, A. Riecher-Rössler, P. Dazzan, X. Chitnis, J. Aston, M. Drewe, U. Gschwandtner, S. Haller, M. Pflüger, E. Rechsteiner, V. Semenin, R.D. Stieglitz, E.W. Radü, P.K. McGuire (2007). Grey matter volume abnormalities in individuals with an At Risk Mental State. Biological Psychiatry, 61, 1148-1156.

K. Dean, E. Walsh, C. Morgan, A. Demjaha, P. Dazzan, K. Morgan, T. Lloyd, P. Fearon, P.B. Jones, R.M. Murray (2006). Aggressive behaviour at first contact with services: findings from the ÆSOP First Episode Psychosis Study. Psychological Medicine, 37, 547-557.

C. Morgan, R. Abdul-Al MPH, J.M. Lappin, P. Jones, P. Fearon, G. Hutchinson, K. Morgan, P. Dazzan, J. Boydell, G. Harrison, T. Craig, R. Mallet, J. Leff, R. Murray (2006). The clinical and social determinants of duration of untreated psychosis in the AESOP first-onset psychosis study. British Journal of Psychiatry, 189: 446-52.

P. Fearon, P.B. Jones, P. Dazzan, C. Morgan, K. Morgan, T. Lloyd, G. Hutchinson, J. Tarrant, A. Fung, J. Holloway, R. Mallett, G. Harrison, J. Leff, R. Murray, on behalf of the ÆSOP study group* (2006). Raised incidence of schizophrenia and other psychoses in ethnic minority groups in three English cities: results from the MRC ÆSOP study. Psychological Medicine 29, 1-10.

P. Dazzan, K. Morgan, K. Orr, G. Hutchinson, X. Chitnis, J. Suckling, P. Fearon, P.K. McGuire, R.M. Mallett, P.B. Jones, J. Leff, R.M. Murray (2005). Different effects of typical and atypical antipsychotics on grey matter in first episode psychosis: the ÆSOP study. Neuropsychopharmacology 4, 765-74.

C.M. Pariante, P. Dazzan, A. Danese, K.D. Morgan, F. Brudaglio, K. Orr, P. Fearon, C. Morgan, G. Hutchinson, C. Pantelis, D. Velakoulis, J. Leff, P.B. Jones, R.M. Murray (2005). Increased pituitary volume in antipsychotic- free and antipsychotic-treated patients of the ÆSOP first-onset psychosis study. Neuropsychopharmacology 30, 1923-31.

C. Morgan, P. Fearon, G. Hutchinson, K. McKenzie, J.M. Lappin, R. Abdul-Al MPH, K. Morgan, P. Dazzan, J. Boydell, G. Harrison, T. Craig, J. Leff, P. Jones, R. Murray (2005). Duration of untreated psychosis and ethnicity in the ÆSOP first-onset psychosis study. Psychological Medicine 36, 239-47.

J.B. Kirkbride, P. Fearon, C. Morgan, P. Dazzan, K. Morgan, J. Tarrant, T. Lloyd, J. Holloway, G. Hutchinson, J.P. Leff, R.M. Mallett, G.L. Harrison, R.M. Murray, P.B. Jones (2005). Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the three-center ÆSOP study. Archives of General Psychiatry, 63:250-8.

B. Garner, C. Pariante, S.J. Wood, D. Velakoulis, L. Phillips, B. Soulsby, W. Brewer, D.J. Smith, P. Dazzan, A.R. Yung, M. van den Buuse, R. Murray, P.D. McGorry, C. Pantelis (2005). An MRI study of pituitary volume in individuals at ultra high risk of developing psychosis. Biological Psychiatry 58, 417-23.

C. Morgan, R. Mallett, G. Hutchinson, H. Bagalkote, K. Morgan, P. Fearon, P. Dazzan, J. Boydell, G. Harrison, R.M. Murray, P.B. Jones, T. Craig, and J. Leff, on behalf of the ÆSOP Study Group (2005). Pathways to care and ethnicity i. sample characteristics and compulsory admission. A Report from the ÆSOP (Aetiology and Ethnicity in Schizophrenia and Other Psychoses) Study. British Journal of Psychiatry 186, 290-6.

C. Morgan, R. Mallett, G. Hutchinson, H. Bagalkote, K. Morgan, P. Fearon, P. Dazzan, J. Boydell, G. Harrison, R.M. Murray, P.B. Jones, T. Craig, and J. Leff, on behalf of the ÆSOP Study Group (2005). Pathways to care and ethnicity ii. source of referral and help-seeking. A Report from the ÆSOP (Aetiology and Ethnicity in Schizophrenia and Other Psychoses) Study. British Journal of Psychiatry 186, 281-9.

T. Lloyd, N. Kennedy, P. Fearon, R. Mallett, J. Leff, G. Harrison, P. Dazzan, K.Morgan, R.M. Murray, P.B. Jones (2005). Incidence of Bipolar Affective Disorder in Three UK Cities: Results from the AESOP Study. British Journal of Psychiatry 186, 126-31.

P. Dazzan, K. Morgan, K. Orr, G. Hutchinson, X. Chitnis, J. Suckling, P. Fearon, J. Salvo, P.K. McGuire, R.M. Mallett, P.B. Jones, J. Leff, R.M. Murray (2004). The structural brain correlates of neurological soft signs in ÆSOP first-episode psychoses study. Brain 127,143-153.

S.E. Connor, V.Ng, C. McDonald, K. Schulze, K. Morgan, P. Dazzan, R.M. Murray (2004). A study of hippocampal shape anomaly in schizophrenia and in families multiply affected by schizophrenia or bipolar disorder. Neuroradiology 46, 523-34.

C.M. Pariante, K. Vassilopoulou, D. Velakoulis, L. Phillips, B. Soulsby, S.J. Wood, W. Brewer, D.J. Smith, P. Dazzan, A.R. Yung, I.M. Zervas, G.N. Christodoulou, R.M. Murray, P.D. McGorry, C. Pantelis (2004). Abnormal pituitary volume in psychosis. British Journal of Psychiatry 185, 5-10.5.

P. Barta & P. Dazzan (2003). Hemispheric surface area: gender and laterality effects. Cerebral Cortex 13, 364-370.

P. Dazzan, D. Bhugra, M.G. Carta, B. Carpiniello (2001). Decision making process for compulsory admission: a study on a group of psychiatrists from Sardinia (Italy). Epidemiologia e Psichiatria Sociale 10, 37-45.

P. Dazzan, D. Bhugra (2000). Decision making process for compulsory admission - A survey of psychiatrists in England. Medicine, Science and the Law 40, 336-34.

D. Bhugra, J. La Grenade, P. Dazzan (2000). Psychiatric in-patients’ satisfaction with services: a pilot study. International Journal of Psychiatry in Clinical Practice 4, 327-332.

M.G. Carta, P. Dazzan, M.A.Reda, B.Carpiniello (2000). Depressive symptoms and occupational role among female groups: a research in a South-East African Village. Psychopathology 33, 240-245.

C.M. Pariante, P. Salis, P. Dazzan, M.G. Carta & B. Carpiniello (1996). Psychosocial outcome of schizophrenic patients in Sardinia, Italy. Psychiatric Services 47, 1266-1267.




last updated: Tuesday, October 14, 2008