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Professor Paul McCrone  PhD, MSc, BA (Hons)
Professor of Health Economics

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Institute of Psychiatry
Box  P024
De Crespigny Park
United Kingdom, SE5 8AF

location 2.15
David Goldberg Centre
departmentsHealth Service and Population Research
alsoCentre for the Economics of Mental Health (CEMH)


Paul McCrone has worked at the Institute of Psychiatry since 1992 and was previously based in the Personal Social Services Research Unit (University of Kent). His main focus is on conducting economic evaluations in the areas of psychosis, neurology, primary care and posttraumatic stress. He works collaboratively with colleagues from the IOP, elsewhere in the UK and internationally and is participating in a number of multi-site European studies. A particular interest is in the use of the net-benefit approach for assessing the cost-effectiveness of new interventions.

teaching activities

Mental Health Service and Population Research » Masters (MSc)
Maudsley Training Programme » MRCPsych


Harding R., Simms V., Penfold S., McCrone P., Moreland S., Downing J., Powell R.A., Mwangi-Powell F., Namisango E., Fayers P., Curtis S., & Higginson I.J. Multi-centred mixed-methods PEPFAR HIV care & support public health evaluation: study protocol. BMC Public Health, 10 (584).

Peters E., Landau S., McCrone P., Cooke M., Fisher P., Steel C., Evans R., Carswell K, Dawson K., Williams S., Howard A., & Kuipers E. (2010) A randomised controlled trial of cognitive behaviour therapy for psychosis in a routine clinical service. Acta Psychiatrica Scandinavica, 122, 302-318.

Gomez B., McCrone P., Hall S., Koffman J., & Higginson I.J. (2010) Variations in the quality and costs of end-of-life care, preferences and palliative outcomes for cancer patients by place of death: the QUALYCARE study. BMC Cancer, 10 (400).

Sharac J., McCrone P., Rushton A., & Monck E. (2010) Enhancing adoptive parenting: a cost-effectiveness analysis. Child and Adolescent Mental Health, in press.

Afuwape SA., Craig TKJ., Harris T., Clarke M., Flood A., Olajide D., Cole E., Leese M., McCrone P., & Thornicroft T. (2010) The Cares of Life Project (CoLP): An exploratory randomised controlled trial of a community-based intervention for black people with common mental disorder. Journal of Affective Disorders, in press.

Evans-Lacko S., Jarrett M., McCrone P., & Thornicroft G. (2010) Facilitators and barriers to implementing clinical care pathways. BMC Health Services Research, 10 (182).

Kaltenthaler E., Cavanagh K., & McCrone P. (2010) Evaluating the role of CCBT within mental health. In: Anthony K., Nagel D.M., & Goss S. (eds). The Use of Technology in Mental Health: Applications, Ethics and Practice. Charles C. Thomas, Publisher: Springfield, IL.

McCrone P., Craig T.K.J., Garety P., & Power P. (2010) Cost-effectiveness of an early intervention service for people with psychosis in south London: the LEO study. British Journal of Psychiatry, 96, 377-382.

Aitchison K.J., Mir A., Shivakumar K., McAllister V.D.M., O’Keane V., & McCrone P. (2010) Costs and outcomes associated with an aripiprazole add-on or switching open-label study in psychosis. Journal of Psychopharmacology, in press.

Norman I.J., Coster S., McCrone P., Sibley A., & Whittlesea C. (2010) A comparison of the clinical effectiveness and costs of mental health nurse supplementary prescribing and independent medical prescribing: a post-test control group study. BMC Health Services Research, 10 (4).

Sharac J., McCrone P., Clement S., & Thornicroft G. (2010) The Economic Impact of Mental Health Stigma and Discrimination: A Systematic Review. Epidemiologia e Psichiatria Sociale, in press.

Howard L.M., Heslin M, Leese M., McCrone P., Rice C., Jarrett M., Spokes T., Huxley P., & Thornicroft G. (2010) The Supported Work and Needs (SWAN) study: a pragmatic randomised controlled trial of supported employment in South London. British Journal of Psychiatry, 96, 404-411.

McCrone P., Knapp M., Henri M., & McDaid D. (2010) The economic impact of initiatives to reduce stigma: demonstration of a modelling approach. Epidemiologia e Psichiatria Sociale, 19, 131-139.

Sharac J., McCrone P., Sabes-Figuera R., Csipke E., Wood A., & Wykes T. (2010) Nurse and patient activities and interaction on psychiatric inpatients wards: a literature review. International Journal of Nursing Studies, doi:10.1016/j.ijnurstu.2010.03.012

Gafoor R., Nitsch D., McCrone P., Craig T.K.J., Garety P.A., Power P., & McGuire P. (2010) Effect of early intervention on 5-year outcome in non-affective psychosis. British Journal of Psychiatry, 196, 372-376.

Higginson I.J., McCrone P., Hart S., Burman R., Silber E., Edmonds P. (2009) Cost effectiveness of a palliative care hospital based service for people with Multiple Sclerosis and their carers. Journal of Pain and Symptom Management, 38, 816-826.

McCrone P., Knapp M., & Dhanasiri S. (2009) Economic impact of services for first episode psychosis: a decision model approach. Early Intervention in Psychiatry, in press.

Moss-Morris R., Dennison L., Yardley L., Landau S., Roche S., McCrone P., & Chalder T. (2009) Protocol for the saMS trial (supportive adjustment for multiple sclerosis): A randomized controlled trial comparing cognitive behavioral therapy to supportive listening for adjustment to multiple sclerosis. BMC Neurology, 9 (45).

Kendrick T., Chatwin J., Dowrick C., Tylee A., Morriss R., Peveler R., Leese M., McCrone P., Harris T., Moore M., Byng R., Brown G., Barthel S., Mander H., Ring A., Kelly V., Wallace V., Gabbay M., Craig T., & Mann A. (2009) Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study. Health Technology Assessment, 13 (22).

Rushton A., Monck E., Leese M., McCrone P., & Sharac J. (2009) Enhancing Adoptive parenting: a randomised controlled trial. Clinical Child Psychology and Psychiatry, in press.

Killaspy H., King M., Wright C., White S., McCrone P., Kallert T., Cervilla J., Raboch J., Onchev G., Mezzina R., Wiersma D., Kiejna A., Ploumpidis D., & Caldas de Almeida J.M. (2009) Study protocol for the development of a European measure of best practice for people with long term mental illness in institutional care (DEMoBinc). BMC Psychiatry, 9:36.

Howard L.M., Heslin M, Leese M., McCrone P., Rice C., Jarrett M., Spokes T., Huxley P., & Thornicroft G. The Supported Work and Needs (SWAN) study: a pragmatic randomised controlled trial of supported employment in South London. British Journal of Psychiatry, in press.

McCrone P. (2009) Capturing the costs of end of life care: comparisons of multiple sclerosis, Parkinson’s disease and dementia. Journal of Pain and Symptom Management, 38, 62-67.

Valmaggia L.R., McCrone P., Knapp M., Woolley J.B., Broome M.R., Tabraham P., Johns L.C., Prescott C., Bramon E., Lappin J., Power P., McGuire P.K. (2009) Economic impact of an early intervention service for people with an at risk mental state for psychosis. Psychological Medicine, 39, 1617-1626.

McCrone P., Killaspy H., Bebbington P., Johnson S., Nolan F., Pilling S., & King M. (2009) The REACT study: cost-consequences analysis of assertive community treatment in North London. Psychiatric Services, 60, 908-913.

McCrone P., Johnson S., Nolan F., Pilling S., Sandor A., Hoult J., McKenzie N., Thompson M., & Bebbington P. (2009) Economic evaluation of a crisis resolution service: a randomised controlled trial. Epidemiologia e Psichiatria Sociale, 18, 54-58.

McCrone P., Patel A., Knapp M., Schene A., Koeter M., Amaddeo F., Ruggeri M., Giessler A., Puschner B., & Thornicroft G. (2009) A comparison of SF-6D and EQ-5D utility scores in a study of patients with schizophrenia. Journal of Mental Health Policy and Economics, 12, 27-31.

Thomas S., McCrone P., Parrott J., & Fahy T. (2009) How do psychiatric patients on prison health care units differ from inpatients in secure psychiatric inpatient units? Psychology, Crime and Law, in press.

McCrone P., Marks I.M., Mataix-Cols D., Kenwright M., & McDonough M. Computer-aided self-exposure therapy for phobia/panic disorder: a pilot economic evaluation. (2009) Cognitive Behaviour Therapy, 38, 91-99.

McCrone P., Johnson S., Nolan F., Sandor A., Hoult J., Pilling S., White IR., Bebbington P., & McKenzie N. (2009) Impact of a crisis resolution team on service costs in the UK. Psychiatric Bulletin, 33, 17-19.

Knapp M., McCrone P., & Leeuwenkamp O. (2008) Associations between negative symptoms, service use patterns, and costs in patients with schizophrenia in five European countries. Clinical Neuropsychiatry, 5, 195-205.

McCrone P., Aitchison K., & Taylor D. (2008) How far have we got in pharmacoeconomics for psychiatry and where are we going? Clinical Neuropsychiatry, 5, 173-174.

McCrone P. (2008) The economics of dementia. British Journal of Healthcare Management, 14, 437-440.

McCrone P., Dhanasiri S., Patel A., Knapp M., & Lawton-Smith S. (2008) Paying the Price: the Cost of Mental Health Care in England to 2026. London, King’s Fund.

Evans-Lacko SE., Jarrett M., McCrone P., & Thornicroft G. (2008) Clinical pathways in psychiatry. British Journal of Psychiatry, 193, 4-5.

Slade M., Gask L., Leese M., McCrone P., Montana C., Powell R., Stewart M., & Chew-Graham C. (2008) Failure to improve appropriateness of referrals to adult community mental health services - lessons from a multi-site cluster-randomised controlled trial, Family Practice, 25, 181-190.

McCrone P, Knapp M, Kennedy T, Seed P, Jones R, Darnley S, & Chalder T. (2008) Cost-effectiveness of cognitive behaviour therapy in addition to mebeverine for irritable bowel syndrome. European Journal of Gastroenterology and Hepatology, 20, 255-263.

Craig TKJ., Johnson S., McCrone P., Afuwape S., Hughes E., Gournay K., White I., Wanigaratne S., Leese M., & Thornicroft G. (2008) Integrated care for co-occurring disorders: psychiatric symptoms, social functioning, and service costs at 18 months. Psychiatric Services, 59, 276-282.

Ridsdale L., Doherty J., McCrone P., & Seed P. (2008) A new practitioner with special interest headache service: observational study. British Journal of General Practice, 58, 478-483.

Thomas S., Slade M., McCrone P., Harty M-A., Parrott J., Thornicroft, & Leese M. (2008) The reliability and validity of the Forensic Camberwell Assessment of Need (CANFOR): a needs assessment for forensic mental health service users. International Journal of Methods in Psychiatric Research, 17, 111-120.

McCrone P., Heslin M., Knapp M., Bull P., & Thompson A. (2008) Multiple sclerosis in the UK: service use, costs, quality of life and disability. PharmacoEconomics, 26, 847-860.

McCrone P. & Knapp M. (2007) Economic evaluation of early intervention services. British Journal of Psychiatry, 191 (suppl 51), s19-s22.

McCrone P. (2007) Health economic measures in schizophrenia research. British Journal of Psychiatry, 191 (suppl 50), s42-s45.

Schene AH., Koeter MWJ, Kikkert MJ, Swinkels JA, McCrone P. (2007) Adjuvant occupational therapy for work-related major depression works: randomized trial including economic evaluation. Psycholological Medicine, 37, 351-362.

McCrone P., Allcock L., & Burn D. (2007) Predicting the cost of Parkinson’s disease. Movement Disorders, 804-812.

Ridsdale L., Clark L.V., Dowson A.J., Goldstein L.H., Jenkins L., McCrone P., Morgan M., & Seed P.T. (2007) How do patients referred to neurologists for headache differ from those managed in primary care? British Journal of General Practice, 57, 388-395.

McCrone P., Marks I.M., Greist J.H., Baer L., Kobak K.A., Wenzel K.W., & Hirsch M.J. (2007) Cost-effectiveness of computer-aided behaviour therapy for obsessive-compulsive disorder. Psychotherapy and Psychosomatics, 76, 249-250.

Järbrink K., McCrone P., Fombonne E., Zandén H., & Knapp M. (2007) Cost-impact of young adults with high-functioning autistic spectrum disorder. Research in Developmental Disabilities, 28, 94-104.

Mohan R., McCrone P., Szmukler G., Micali N., Afuwape S., & Thornicroft G. (2006) Ethnic differences in mental health service use among patients with psychotic disorders. Social Psychiatry and Psychiatric Epidemiology, 41, 771-776.

Kennedy T.M., Chalder T., McCrone P., Darnley S., Knapp M., Jones R.H., & Wessely S. (2006) Cognitive behavioural therapy in addition to antispasmodic therapy for irritable bowel syndrome in primary care: randomised controlled trial. Health Technology Assessment, 10 (19).
Kucukalic A., Bravo-Mehmedbašic A., Fadilpašic S, Priebe S., Gavrilovic-Jankovic J., McCrone P., Schützwohl M., Ljubotina D., Franciškovic T., Lecic-Toševski D. (2006) Comparison of sociodemographic characteristics of patients with PTSD in the four countries of former Yugoslavia following the war. Medarh, 60, 230-233.

Bhui K., Craig T., Mohamud S., Warfa N., Stansfeld S., Thornicroft G., Curtis S., & McCrone P. (2006) Mental disorders among Somali refugees. Developing culturally appropriate measures and assessing socio-cultural risk factors. Social Psychiatry and Psychiatric Epidemiology, in press.

Frangou S., Lewis M., & McCrone P. (2006) Efficacy of ethyl-eicosapentaenoic acid in bipolar depression: randomised double-blind placebo-controlled study. British Journal of Psychiatry, 188, 46-50.

McCrone P., Thornicroft G., Boyle S., Knapp M., & Aziz F. (2006) The development of a Local Index of Need (LIN) and its use to explain variations in Social Services expenditure on mental health care in England. Health and Social Care in the Community, 14, 254-263.

Slade M., McCrone P., Kuipers E., Leese M., Cahill S., Parabiaghi A., Priebe S., Thornicroft G. Use of standardised outcome measures in adult mental health services: randomised controlled trial. (2006) British Journal of Psychiatry, in press.

Järbrink K., McCrone P., Fombonne E., Zandén H., & Knapp M. (2006) Cost-impact of young adults with high-functioning autistic spectrum disorder. Research in Developmental Disabilities, in press.

Warfa N., Bhui K., Craig T., Curtis S., Mohamud S., Stansfeld S., McCrone P., & Thornicroft G. (2006) Post migration geographical mobility, mental health and health service utilisation among Somali refugees in the UK: A qualitative study. Health and Place, in press.

McCrone P., Hallam A., Knapp M., Swaray F., Nazir A., Leff J., & Szmidla A. (2006) Service use and costs of supporting the most socially disabled patients in a hospital reprovision programme – A two-hospital comparison. Social Psychiatry and Psychiatric Epidemiology, 41, 656-661.

McCrone P., Iliffe S., Levin E., Kharicha K., & Davey B. (2005) Joint working between social and health services in the care of older people in the community: a cost study. Journal of Integrated Care, 13, 34-43.

McCrone P., Knapp M., & Fombonne E. (2005) The Maudsley long-term follow-up of child and adolescent depression: predicting costs in adulthood. European Child and Adolescent Psychiatry, in press.

Thomas S., Leese L., Walsh E., McCrone P., Moran P., Burns T., Creed F., Tyrer P., & Fahy T. (2005) A comparison of statistical models in predicting violence in psychotic illness. Comprehensive Psychiatry, 46, 296-303.

Howard L., Wessely S., Leese M., Page L., McCrone P., Husain K., Tong J., & Dowson A. (2005) Are investigations anxiolytic or anxiogenic? A randomised controlled trial of neuroimaging to provide reassurance for chronic daily headache. Journal of Neurology, Neurosurgery and Psychiatry, in press.

McCrone P., Szmukler G., & Kuipers E. (2005) Service use and cost associated with caring for people with serious mental illness. Journal of Mental Health, 14, 37-47.

Lam D., McCrone P., Wright K., & Kerr N. (2005) Cost-effectiveness of 30-month study of relapse prevention cognitive therapy for bipolar disorder. British Journal of Psychiatry, 186, 500-506.

McCrone P., Weeramanthri T., Knapp M., Rushton A., Trowell J., Miles G., & Kolvin I. (2005) Cost-effectiveness of individual versus group psychotherapy for sexually abused girls. Child and Adolescent Mental Health, 10, 26-31.

McCrone P., Bhui K., Craig T., Mohamud S., Warfa N., Stansfeld S. A., Thornicroft G., & Curtis S. (2005) Mental health needs, service use and costs among Somali refugees in the UK. Acta Psychiatrica Scandinavica, 111, 351-357.

Najim H. & McCrone P. (2005) The Camberwell Assessment of Need: comparison of assessments by staff and patients in an inner-city and a semi-rural community area. Psychiatric Bulletin, 29, 13-17.

Knapp M., Barrett B., Romeo R., McCrone P., Byford S., Beecham J., Patel A., & Simon J. (2005) An international review of cost-effectiveness studies for mental disorders. Disease Control Priorities Project Working Paper No. 36.

last updated: Wednesday, November 03, 2010