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Dr Paolo Fusar-Poli  MD, PhD
Clinical Senior Lecturer
Consultant in Adult Psychiatry
OASIS - South London and Maudsley NHS Foundation Trust

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Institute of Psychiatry
Box  P063
De Crespigny Park
United Kingdom, SE5 8AF

location 5ht Floor
Department of Psychosis Studies
departmentsPsychosis Studies

activities and interests

-Neuroimaging correlates of prodromal psychosis. This work involves people at ultra high cliincal risk for psychosis and is the focus of my doctoral work. I have published extensively on this subject using functional, structural, chemical neuroimaging or multimodal imaging studies combining different techniques.

-Pharmacological neuroimaging. Studies which combine functional neuroimaging with a pharmacological challenge, which provide a means of examining the influence of neurotransmitters such as 5HT or cannabinoids on cognitive and emotional processing.

-Philosophy of science. My aim is to focus on philosophical issues and methodological limits raised by neuroimaging techniques and by a cognitive neuroscience of psychopathology. In addition I’ve developed an interest into history of psychiatry.



To date Dr. Fusar-Poli has published about 200 PubMed papers (for the complete and updated list see the link below here)

-Fusar-Poli P, Borgwardt S, Bechdolf A, Addington J, Riecher-Rössler A, Schultze-Lutter F, Keshavan M, Wood S, Ruhrmann S, Seidman LJ, Valmaggia L, Cannon T, Velthorst E, De Haan L, Cornblatt B, Bonoldi I, Birchwood M, McGlashan T, Carpenter W, McGorry P, Klosterkötter J, McGuire P, Yung A. The psychosis high-risk state: a comprehensive state-of-the-art review.
JAMA Psychiatry. 2013 Jan;70(1):107-20.

-Fusar-Poli P, Byrne M, Badger S, Valmaggia LR, McGuire PK. Outreach and support in South London (OASIS), 2001-2011: Ten years of early diagnosis and treatment for young individuals at high clinical risk for psychosis.
Eur Psychiatry. 2012 Nov 5. doi:pii: S0924-9338(12)00098-3. 10.1016/j.eurpsy.2012.08.002. [Epub ahead of print]

-Fusar-Poli P, Deste G, Smieskova R, Yung A, Howes O, Stieglitz R, Vita A, McGuire P, Borgwardt S. Congnitive functioning in prodromal psychosis: a meta-analysis. Archives of General Psychiatry 2012 (IF=16) 2012 Jun;69(6):562-71.

-Fusar-Poli P, Nelson B, Valmaggia L, Yung AR, McGuire PK. Comorbid Depressive and Anxiety Disorders in 509 Individuals With an At-Risk Mental State: Impact on Psychopathology and Transition to Psychosis.
Schizophr Bull. 2012 Nov 22. [Epub ahead of print]

-Fusar-Poli P, Bonoldi I, Yung AR, Borgwardt S, Kempton M, Barale F, Caverzasi E, McGuire P. Predicting psychosis: a meta –analysis of transition outcomes in individuals at high clinical risk. Archives of General Psychiatry (IF=16) 2012;69(3):220-9.

-Fusar-Poli P, Bechdolf A, Taylor MJ, Bonoldi I, Carpenter WT, Yung AR, McGuire P. At Risk for Schizophrenic or Affective Psychoses? A Meta-Analysis of DSM/ICD Diagnostic Outcomes in Individuals at High Clinical Risk.
Schizophr Bull. 2012 May 15. [Epub ahead of print]

-Fusar-Poli P, Rubia K, Giorgio R, Sartori G, Balottin U. Striatal dopamine transporter alterations in ADHD: pathophysiology or adaptation to psychostimulants? A meta-analysis. American Journal of Psychiatry (IF=12.5) 2012;169(3):264-72.

-Fusar-Poli P, Yung AR. Should attenuated psychosis syndrome be included in the DSM5? The debate. The Lancet (IF=33.6) 2012;379(9816):591-2.

-Fusar-Poli P, Meyer-Lindenberg A. Striatal presynaptic dopamine in schizophrenia, part I: meta-analysis of dopamine active transporter (DAT) density. Schizophrenia Bulletin (IF=9), 2013 Jan;39(1):22-32. doi: 10.1093/schbul/sbr111. Epub 2012 Jan 26.

-Fusar-Poli P, Meyer-Lindenberg A. Striatal presynaptic dopamine in schizophrenia, part II: meta-analysis of [(18)F/(11)C]-DOPA PET studies. 2013 Jan;39(1):33-42. doi: 10.1093/schbul/sbr180. Epub 2012 Jan 26.

-Fusar-Poli P, Stone JM, Broome MR, Valli I, Mechelli A, McLean MA, Lythgoe DJ, O’Gorman RL, Barker G, McGuire P. Thalamic glutamate levels predict cortical response during executive functioning in subjects at high risk for psychosis. Archives of General Psychiatry (IF=16) 2011;(9):881-90.

-Fusar-Poli P, Howes O, Allen P, Broome M, Valli I, Asselin I, Montgomery C, Grasby P, McGuire P. Abnormal prefrontal activation directly related to pre-synaptic striatal dopamine dysfunction in people at clinical risk for psychosis. Molecular Psychiatry (IF=12.53) 2011;16(1):67-75.

-Fusar-Poli P, Radua J, McGuire P, Borgwardt S. Neuroanatomical Maps of Psychosis Onset: Voxel-wise Meta-Analysis of Antipsychotic-Naive VBM Studies. Schizophrenia Bulletin 2011 (IF=9) 2012 Nov;38(6):1297-307. doi: 10.1093/schbul/sbr134. Epub 2011 Nov 10.

-Fusar-Poli P, Borgwardt S, Crescini A, Deste G, Kempton MJ, Lawrie S, Mc Guire P, Sacchetti E.Neuroanatomy of vulnerability to psychosis: a voxel-based meta-analysis. Neuroscience and Biobehavioral Reviews (IF=8). 2011 Apr;35(5):1175-85.

-Fusar-Poli P, Broome MR, Matthiasson P, Woolley JB, Mechelli A, Johns LC, Tabraham P, Bramon E, Valmaggia L, Williams SC, McGuire P. Prefrontal function at presentation directly related to clinical outcome in people at ultrahigh risk of psychosis. Schizophrenia Bulletin (IF=9) 2011 Jan;37(1):189-98.

-Fusar-Poli P, Howes O, Allen P, Broome M, Valli I, Asselin I, Montgomery C, Grasby P, McGuire P. Abnormal frontostriatal interactions in people with prodromal signs of psychosis: a multimodal imaging study. Archives of General Psychiatry (IF=15.9) 2010;67(7):683-691.

-Fusar-Poli P, Crippa J, Bhattacharyya S, Borgwardt S, Allen P, Martin-Santos R, Seal M, O’Carrol C, Surguladze S, Atakan Z, Zuardi AW, McGuire P. Distinct effects of D9-Tetrahydrocannabinol and cannabidiol on neural activation during emotional processing. Archives of General Psychiatry 2009 (IF= 15.9) 66(1):95-105.

-Bhattacharyya S, P Fusar-Poli, S Borgwardt, R Martin-Santos, C Nosarti, C O’ Carroll, P Allen, M Seal, P Fletcher,JA Crippa, V Giampietro, A Mechelli, Z Atakan, P McGuire. Delta-9-Tetrahydrocannabinol modulates medial temporal and striatal function in humans: a neural basis for the effects of cannabis on learning and psychosis. Archives of General Psychiatry (IF= 15.9) 2009;66(4):442-51.

-McGuire P, Howes OD, Stone J, Fusar-Poli P.Functional neuroimaging in schizophrenia: diagnosis and drug discovery. Trends in Pharmacological Sciences. 2008 (IF=13) 29(2):91-8.

-P Fusar-Poli, L Valmaggia, P McGuire. Can antidepressants prevent psychosis? The Lancet 2007 (IF 26), Nov 24;370(9601):1746-8.

-Fusar-Poli P, Perez J, Broome M, Borgwardt S, Placentino A, Caverzasi E, Cortesi M, Veggiotti P, Politi P, Barale F, McGuire P. Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-anaysis. Neuroscience and Biobehavioural Reviews (IF=8) 2007;31(4):465-84. .

-Fusar-Poli P. Roger Keith "Syd" Barrett (1946-2006). American Journal of Psychiatry. 2007 Jul;164(7):1028.

last updated: Tuesday, April 16, 2013