Professor Ian W Craig BSc (Hons) Biochemistry; PhD Biochemistry
Professor of Molecular Behavioural Genetics
Director of Laboratories
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| contact this person | |
| tel | 0207 848 0018 |
| fax | 0207 848 0866 |
| address | Institute of Psychiatry |
| location | C1.13 MRC, SGDP Centre |
| departments | Social, Genetic and Developmental Psychiatry (IRG) Social, Genetic and Developmental Psychiatry Centre (MRC) |
| also | GENDEP |
biography
I am Head of the Molecular Genetics Section of the SGDP Research Centre with responsibilities for the co-ordination of molecular genetic approaches within a range of collaborative projects (see below). Previous to my joining to the Institute of Psychiatry, I worked for many years in the Genetics Unit at the Department of Biochemistry at Oxford University and was appointed to the titular post of Professor in Genetics there in 1997. My group was involved in one of the early positional cloning successes (a gene for X-linked blindness and mental retardation) and in the characterisation of additional genes implicated in a range of human disorders. I was appointed a Fellow of St Catherine’s College, Oxford in 1972 and retired from there in 2009. My interests in human gene mapping have involved participation in the development of the Genome Database, GDB, as a Chromosome Editor and most recently through elections to the Human Genome Organisation, HUGO, Council (2000-2003; 2003-2006) and appointment as a Trustee to HUGO (London Ltd) in 2010.
Currently, I am involved in a variety of projects, many of which depend on fast and efficient genotyping of simple sequence repeat variants and single nucleotide polymorphisms as applied to whole genome scanning for association with QTLs implicated in a range of behaviours and disorders. These include: cognition (g), addiction, aggression, anxiety and depression. With other members of the Section, I am exploring improved methods for high throughput genotyping based on DNA pooling with micro-arrays and the co-ordinated examination of genotypes for neurotransmitter pathway genes in a variety of behaviours. I have a particular interest in the relevance to behaviour genetics of inactivation and potential imprinting of the X chromosome and generally in the contribution of the X- and Y-chromosomes to sex differences in behaviour.
Current Collaborations
Cognition – Genome screening for QTLs implicated in cognition (g) - with Professor Plomin.
Unipolar Depression Studies with Professors Anne Farmer, Cathryn Lewis and Peter McGuffin.
Dunedin Longitudinal Study in the project led by Professors Temi Moffit and Avshalom Caspi (At the SGDP Research Centre and Dunedin).
GENDEP Pharmacogenomic investigation on Depression. An EU Multicentre Study.
publications
15 Key Papers 1992-present
Uher, R., Huezo-Diaz, P., Perroud, N., Smith, R., Rietchel, M., Mors, O., Hauser, J., Maier, W., Kozel, D., Henigsberg, N., Barreto, M., Placentino, A., Dernovsek, M.Z., Schulze, T.G., Kalember, P., Zobel, A., Czerski, P.M., Larsen, E.R., Sourey. D., Giovannini, C., Gray, J.M., Lewis, C.M., Farmer, A., Aitchison, K.J., McGuffin, P., and Craig, I. (2010). Genetic predictors of response to antidepressants in the GENDEP project. The Pharmacogenomics Journal, accepted for publication.
Cohen-Woods, S., Gaysina, D., Craddock, N., Farmer, A., Gray, J., Gunasinghe, C., Hoda, F., Jones, L., Knight, J., Korszun, A., Owen, M.J., Sterne, A., Craig, I.W. and McGuffin, P. (2009). Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder. Hum Mol Genet 18, 1504-9.
Caspi, A., Moffit, T.E., Cannon, M., McClay, J., Murray, R., Harrington, H.L., Taylor, A., Arseneault, L., Williams, B., Braithwaite, A., Poulton, R. and Craig, I. (2005). Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the COMT gene: longitudinal evidence of a gene X environment interaction. Biol Psychiatry 57, 1117-1127.
Butcher, L., Meaburn, E., Knight, J., Sham, P., Schalkwyk, L., Craig I.W. & Plomin R. (2005). SNPs, microarrays, and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. Hum Mol Genet 14, 1315-1325.
Eley, T.C., Sugden, K., Corsico, A., Gregory, A., Sham, P., McGuffin, P., Sterne, A., Plomin, R. and Craig, I.W. (2004). Gene-environment interaction analysis of serotonin system markers with adolescent depression. Mol Psychiatry 9, 908-915.
Caspi, A., Sugden, K., Moffitt, T.E., Taylor, A., Craig, I.W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A. and Poulton, R. (2003). Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301, 386-389.
Caspi, A., McClay, J., Moffitt, T.E., Mill, J., Martin, Craig, I.W., Taylor, A. Poulton, R. (2002). Role of Genotype in the cycle of violence in maltreated children. Science 297, 851-854.
Sham, P., Bader, J.S., Craig, I., O’Donovan, M. and Owen, O. (2002) DNA pooling: a tool for large-scale association studies. Nat Rev Genet 3, 862-871.
Koch H.G., McClay J., Loh E.-W., Higuchi S., Ball, D., Zhao, J-H., Sham, P. and Craig I.W. (2001). Allele association studies with SSR and SNP markers at known physical distances within a 1MB region embracing the ALDH2 locus in the Japanese, demonstrates linkage disequilibrium extending up to 400 Kb. Hum Mol Genet 9, 2993-2999.
Tanaka, K., Fisher S. and Craig, I.W. (1999). Characterisation of novel promoter and enhancer elements of the mouse homologue of the Dent’s disease gene, CLCN5, implicated in X-linked hereditary nephrolithiasis. Genomics 58, 281-292.
Lloyd, S.E., Pearce, S.H.S., Fisher, S., Steinmeyer, K., Schwappach, B., Scheinman, S.I. Harding, B., Bolino, A., Devoto, M., Goodyer, P., Rigden, S.P.A., Wrong, O., Jentsch., T.J., Craig, I.W. and Thakker, R. (1996). Mutations in the chloride channel ClC-5 are associated with X-linked hypercaliuric nephrolithiasis. Nature 379, 446-449.
Fisher, S.E., van Bakel, I., Lloyd, S.E., Pearce, S.H.S., Thakker, R. and Craig, I.W. (1995). Cloning and characterisation of CLCN5, the human kidney chloride channel gene implicated in X-linked hereditary nephrolithiasis. Genomics 29, 598-606.
Fisher, S.E., Black, G.C.M., Lloyd, S.E., Hatchwell, E., Wrong, O., Thakker, R.V. and Craig, I.W. (1994). Isolation and partial characterisation of a chloride channel gene which is expressed in kidney and is a candidate for Dent’s disease (an X-linked heriditary nephrolithiasis). Hum Mol Genet 3, 2053-2059.
Chen, Z-Y., Battinelli, E.M., Fielder, A., Bundey, S., Sims, K., Breakfield, X.O. and Craig, I.W. (1993). Identification of a mutation in the Norrie disease gene (NDP) in affected members of a family with X-linked familial exudative vitreoretinopathy. Nat Genet 5, 180-183.
Chen, Z-Y., Hendriks, R.W., Jobling, M.A., Powell, J.F., Breakfield, X.O., Davies, K.E. and Craig, I.W. (1992). Isolation and characterisation of a gene implicated in Norrie disease. Nat Genet 1, 204-208.
PUBLICATIONS since 2005
Loat, C.S., Asbury, K., Galsworthy, M.J., Plomin, R. and Craig, I.W. (2004). X inactivation as a source of behavioural differences in monozygotic female twins. Twin Res 7, 54-61.
Craig, I.W., Mill, J., Craig, G.M., Loat, C. and Schalkwyk, L.C. (2004). Application of micro-arrays to the analysis of the inactivation status of human X-linked genes expressed in lymphocytes. Eur J Hum Gen 12, 639-646.
Craig, I.W., Harper, E. and Loat, C. (2004). The genetic basis for sex differences in human behaviour: role of the sex chromosomes. Ann Hum Genet 68, 269-284.
Nash, M.W., Huezo-Diaz, P., Williamson, R.J., Sterne, A., Purcell, S., Hoda, F., Cherny, S.S., Abecasis, G.R., Prince, M., Gray, J.A., Ball, D., Asherson, P., Mann, A., Goldberg, D., McGuffin, P., Farmer, A., Plomin, R., Craig, I.W. and Sham, P.C. (2004). Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships. Hum Mol Genet 13, 2173-2182.
Nash, M.W., Sugden, K., Huezo-Diaz, P., Williamson, R., Sterne, A., Purcell, S., Sham, P.C. and Craig, I.W. (2005). Association analysis of monoamine genes with depression and anxiety-related traits in a selected community sample of siblings. Am J Med Genet B: Neuropsychiatr Genet 135, 33-37.
Eley, T.C., Sugden, K., Corsico, A., Gregory, A., Sham, P., McGuffin, P., Sterne, A., Plomin, R. and Craig, I.W. (2004). Gene-environment interaction analysis of serotonin system markers with adolescent depression. Mol Psychiatry 9, 908-915.
Butcher, L.M., Meaburn, E., Liu, L., Fernandes, C., Hill, L., Al-Chalabi, A., Plomin, R., Schalkwyk, L. and Craig, I.W. (2004). Genotyping pooled DNA on microarrays: A systematic genome screen of thousands of SNPs in large samples to detect QTLs for complex traits. Behav Genet 34, 549-555.
Craig, I.W., Meaburn, E., Butcher, L., Hill, L. and Plomin, R. (2004). SNP genotyping in DNA pools. In: Pharmacogenomics: Methods and Protocols (ed. F. Innocenti). Humana Press.
Curran, S., Purcell, S., Craig, I., Asherson, P. and Sham, P (2004). The serotonin transporter gene as a QTL for ADHD. Am J Med Genet B Neuropsychiatr Genet 134, 42-47.
D’Souza, U.M., Russ, C., Tahir, E., Browes, C., Mill, J., McGuffin, P., Asherson, P.J. and Craig, I.W. (2004). Functional effects of a tandem duplication polymorphism in the 5’flanking region of the DRD4 gene. Biol Psychiatry 56, 691-697.
Butcher, L., Meaburn, E., Dale, P.S., Sham, P., Schalkwyk, L., Craig, I.W. and Plomin, R. (2004). Association analysis of mild mental impairment using DNA pooling to screen 432 brain-expressed single nucleotide polymorphisms. Mol Psychiatry 10, 384-392.
Harlaar, N., Butcher, L., Meaburn, E., Sham, P., Craig, I.W. & Plomin, R. (2004). A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds. J Child Psychol Psychiatry 46, 1030-1038.
Mill, J., Xu, X., Ronald, A., Curran, S., Price, T., Knight, J., Craig, I., Sham, P., Plomin, R. and Asherson, P. (2004). QTL analysis of candidate genes alleles associated with ADHD in five genes: DRD4, DAT1, DRD5, SNAP-25 and 5HT1B. Am J Med Genet B Neuropsychiatr Genet 133, 68-73.
Aitchison, K.J., Basu, A., McGuffin, P. and Craig, I. (2005). Psychiatry and the ‘new genetics’: hunting for genes for behaviour and drug response. Brit J Psychiatry 186, 91-92.
Craig, I.W. (2005). The role of monoamine oxidase A, MAOA, in the aetiology of antisocial behaviour: the importance of gene environment interactions. In: Molecular Mechanisms influencing aggressive behaviours: Novartis Foundation Symposium 268 (eds. G. Bock and J. Goode), pp. 227-37. Chichester: John Wiley & Sons Ltd.
Simpson, C., Knight, J., Butcher, L., Hansen, V., Meaburn, E., Schalkwyk, L., Craig, I., Powell, J., Sham, P. and Al-Chalabi, A. (2005). A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays. Nucleic Acids Res 33:e25.
Xu, X., Knight, J., Brookes, K., Mill, J., Sham, P., Craig, I., Taylor E. and Asherson, P (2005). DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: no evidence for association. Am J Med Genet B Neuropsychiatr Genet 134, 115-118.
Mill, J., Asherson, P., Craig, I. and DeSouza, U. (2005). Transient expression analysis of allelic variants of a VNTR in the dopamine transporter gene (DAT1). BMC Genet 6: 3.
Butcher, L., Meaburn, E., Knight, J., Sham, P., Schalkwyk, L., Craig, I.W. & Plomin R. (2005). SNPs, microarrays, and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. Hum Mol Genet 14, 1315-1325.
Meaburn, E., Butcher, L.M., Liu, L., Fernandes, C., Hansen, V., Al-Chalabi, A., Plomin, R., Craig, I. and Schalkwyk, L. (2005). Genotyping DNA pools on microarrays: Tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics 6: 52.
Caspi, A., Moffit, T.E., Cannon, M., McClay, J., Murray, R., Harrington, H.L., Taylor, A., Arseneault, L., Williams, B., Braithwaite, A., Poulton, R. and Craig, I. (2005). Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the COMT gene: longitudinal evidence of a gene X environment interaction. Biol Psychiatry 57, 1117-1127.
Eley, T.C. and Craig, I.W. (2005). Introductory guide to the language of molecular genetics. J Child Psychol Psychiatry 46, 1039-1041.
D’Souza, U. and Craig, I.W. (2006). Functional Polymorphisms in Dopamine and Serotonin Pathway Genes. Hum Mutat 27, 1-13.
Loat, C.S., Craig, G.M., Plomin, R. and Craig, I.W. (2006). Investigating the relationship between FMR1 allele length and cognitive ability in children: a subtle effect of the normal allele range on the normal ability range? Ann Hum Genet 70, 555-565.
Brookes, K,. Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., Aneey, R., Franke, B., Gill, M., Ebstein, R., Buitelaar, J., Sham, P., Campbell, D., Knight, J., Andreou, P., Altink, M.R., Arnold, R., Boer, F., Buschgens, C., Butler, L., Christiansen, H., Feldman, L., Fleischman, K., Fliers, E., Howe-Forbes, R., Goldfarb, A., Heise, A., Gabrials, I., Korn-Lubetzki, I., Marco, R., Medad, S., Minderaa, R., Mulas, F., Mailler, U., Mulligan, A., Rabin, K., Rommelse, N., Sethna, V., Sorohan, J., Uebel, H., Psychogiou, L., Weeks, A., Barrett, R., Craig, I., Banaschewski, T., Sonuga-Barke, E., Eisenberg, J., Kuntsi, J., Manor, I., McGuffin, P., Miranda, A., Oades, R.D., Plomin, R., Roeyers, H., Rothenberger,A., Sergeant, J., Steinhausen, H-C., Taylor, E., Thompson, M., Faraone, S.V., Asherson, P. and Johansson, L. (2006). The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes. Mol Psychiatry 11, 934-953.
Craig, I. and Plomin, R. (2006). Quantitative trait loci for IQ and other complex traits: single nucleotide polymorphism genotyping using pooled DNA and microarrays. Genes Brain Behav 5, 32-37.
Dempster, E.L., Mill, J., Craig, I.W. and Collier, D.A. (2006). The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression. BMC Med Genet 7, 10-17.
Plomin, R., Kennedy, J.K.J. and Craig, I.W. (2006). The quest for quantitative trait loci associated with intelligence. Intelligence 34, 513-526.
Kim-Cohen, J., Caspi, A., Taylor, A., Williams, B., Newcombe, R., Craig, I.W. and Moffit, T.E. (2006). MAOA, mal-treatment and gene-environment interaction predicting children’s mental health: new evidence and a meta-analysis. Mol Psych 11, 903-913.
Mill, J., Dempster, E., Caspi, A., Williams, B., Moffitt, T. and Craig, I. (2006). Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyl transferase (COMT) gene. Am J Med Genet B Neuropsychiat Genet 141, 421-425.
Craig, I.W. (2006). Interakcje czynnikow genetyczych i srodowiskowych w rozwoju agresji. In: Psychospoleczne I Neurobiologiczne aspekty agresji. Wydawnictwo Instytutu Psychologii Pan, Warszawa 2005, pp 121-129. (In Polish)
Guindalini, C., Howard, M., Haddley, K., Laranjeira, R., Collier, D., Ammar, N., Craig, I.W., O’Gara, C., Bubb, V.J., Greenwood, T., Kelsoe, J., Asherson, P., Murray, R., Castelo, A., Quinn, J.P., Valada, H. and Breen, G. (2006). Dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample. Proc Natl Acad Sci USA. 103, 4552-4557.
Mill, J., Caspi, A., Williams, B.S., Craig, I., Alan Taylor, A., Polo-Tomas, M., W. Berridge, C.W., Poulton, R. and Moffitt, T.E. (2006). Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts. Arch Gen Psychiatry 63, 462-469.
Fowler, J.S., Alia-Klein, N., Kriplani, A., Logan, J., Williams, B., Zhu, W., Craig, I.W., Telang, F., Goldstein, R., Volkow, N.D., Vaska, P., Wang, G-W. (2007). Evidence that brain MAO A activity does not correspond to MAO A genotype in healthy male subjects. Biol Psych 62, 355-358.
Craig, I.W. (2007). The importance of stress and genetic variation in human aggression. Bioessays 29, 227-236.
Craig, I.W. and Loat, C. (2007). The evolutionary genetics of morality. In: The Science of Morality. Conference Proceedings. Royal College of Physicians (ed. G. Walker), pp. 33-50.
Craig, I.W. (2007). Genetic Polymorphisms in stress response. In: Encyclopedia of Stress, 2nd Edition (ed. G. Fink), Vol 2 pp. 135-140. Oxford: Elsevier.
Huezo-Diaz, P. and Craig, I.W. (2007). Monoamine Oxidase. In: Encyclopedia of Stress, 2nd Edition (ed. G. Fink), Vol 2 pp. 761-764. Oxford: Elsevier.
Caspi, A., Williams, B., Kim-Cohen, J., Craig, I.W., Milne, B., Poulton, R., Schalkwyk, L., Taylor, A., Werts, H. and Moffitt, T.E. (2007). Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. Proc Natl Acad Sci USA . www.pnas.org/cgl/doi/10.1073/pnas.0704292104.
Craig, I.W. and Loat, C. (2007). Genetische Grundlagen von Geschlechtsunterschieden. In: ZNS-Funktionen Gehirn und Geschlecht: Neurowissenschaft des kleinen Unterschieds zwischen Mann und Frau. (CNS- Functions brain and gender: Neuroscience of the small difference between man and woman) (eds. S. Lautenbacher, O. Gunturkun and M. Hausmann), pp 63-83.
Alia-Klein, N., Goldstein, R.Z., Kriplani, A., Logan, J., Tomasi, D., Williams, B., Telang, F., Shumay, E., Biegon, A., Craig, I.W., Henn, F., Wang, G.J., Volkow, N.D., and Fowler, J.S. (2008). Brain monoamine oxidase a activity predicts trait aggression. Journal of Neuroscience 28, 5099-5104.
D’Souza, U. M. and Craig, I. (2008). Functional Genetic Polymorphisms in Serotonin and Dopamine Gene Systems and their significance in behavioural disorders. G. Di Giovanni, V. Di Matteo & E. Esposito (Eds.)
Progress in Brain Research, Vol. 172
Breen, G., Collier, D., Craig, I. and Quinn, J. (2008) Variable number tandem repeats as agents of functional regulation in the genome. Engineering in Medicine and Biology Magazine 27, 103-108.
Butcher, L.M., Davis, O.S.P., Craig, I.W., et al., (2008). Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays. Genes Brain and Behavior, 2008. 7(4): p. 435-446.
Gaysina, D., Cohen-Woods, S., etc Craig, I.W. (2008). Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a Bipolar Case-Control Study (BACCS). Neuropsychiatric Genetics In Press
Cohen, S., Pirlo, K., Schosser, A., Gaysina, D., Craddock, N., Korszun, A., Owen, M., Craig, I., Farmer, A., and McGuffin, P. (2008). The depression case control study in the whole genome association era: results and implications for the future. Nice, FRANCE: Elsevier Science Bv.
Meaburn, E.L., Harlaar, N., Craig, I.W., Schalkwyk, L.C. and Plomin, R. (2008). Quantitative trait locus association scan of early reading disability and ability using pooled DNA and 100K SNP microarrays in a sample of 5760 children. Mol Psych 13, 729-740.
Rosa, A., Picchioni, M.M., Kalidindi, S., Loat, C.S., Knight, J., Toulopoulou, T., Vonk, R., van der Schot, A.C., Nolen, W., Kahn, R.S., McGuffin, P., Murray, R.M. and Craig, I.W. (2008). Differential Methylation of the X-chromosome is a Possible Source of Discordance for Bipolar Disorder Female Monozygotic Twins. Am J Med Genet B Neuropsychiatr Genet 147, 459-62.
Alia-Klein, N., Goldstein, R.Z., Kriplani, A., Logan, J., Tomasi, D., Williams, B., Telang, F., Shumay, E., Biegon, A., Craig, I.W., Henn, F., Wang, G-W., Volkow, N.D. and Fowler, J.S. (2008). Brain monoamine oxidase A activity predicts trait aggression. The Journal of Neuroscience 28, 5009-5104.
O’Gara, C., Knight, J., Stapleton, J., Luty, J., Neale, J., Nash, M., Huezo-Diaz, P., Hoda, F., Cohen, S., Sutherland, G., Collier, D., Sham, P., Ball, D., McGuffin, P. and Craig, I. (2008). Association of the serotonin transporter gene, neuroticism and smoking behaviour. J Hum Genet 53, 239-246.
Gaysina, D., Cohen, S., Craddock, N., Farmer, A., Hoda, F., Korszun, A., Owen, M.J., Craig, I.W. and McGuffin, P. (2008) No association with the 5,10-methylenetetrahydrofolate reductase gene and major depressive disorder: Results of the depression case control (DeCC) study and a meta-analysis. Am J Med Genet B Neuropsychiatr Genet 147B, 699-706.
Loat, C.S., Curran, S., Lewis, C.M., Abrahams, B., Duvall, J., Geschwind, D., Bolton, P., and Craig, I.W. (2008). Methyl – CpG – binding protein (MECP2) polymorphisms and vulnerability to autism. Genes Brain Behav 7, 754-760.
Loat, C.S., Haworth, C.M.A., Plomin, R. and Craig, I.W. (2008) A model incorporating potential skewed X-inactivation in MZ girls suggests that X-Linked QTLs exist for several social behaviours including Autism Spectrum Disorder. Ann Hum Genet 72, 742-751.
D’Souza, U.M. and Craig, I.W. (2008). Functional Genetic Polymorphisms in Serotonin and Dopamine Gene Systems and their significance in behavioural disorders. In: G. Di Giovanni, V. Di Matteo & E. Esposito (Eds.) Progress in Brain Research, Vol. 172, pp. 73-98.
Alia-Klein, N., Kriplani, A., Pradhan, K., Ma, J.Y., Logan, J., Williams, B., Craig, I.W., Telang, F., Tomasi, D., Goldstein, R.Z., Wang, G.J., Volkow, N.D. and Fowler, J.S. (2008) The MAO-A genotype does not modulate resting brain metabolism in adults. Psychiat Res-Neuroim 164, 73-76.
Alia-Klein, N., Goldstein, R.Z., Tomasi, D., Woicik, P.A., Moeller, S.J., Williams, B., Craig, I.W., Telang, F., Biegon, A., Wang, G.J., Fowler, J.S., and Volkow, N.D. (2009). Neural Mechanisms of Anger Regulation as a Function of Genetic Risk for Violence (vol 9, pg 385, 2009). Emotion 9, 487-487.
Alia-Klein, N., Goldstein, R.Z., Tomasi, D., Woicik, P.A., Moeller, S.J., Williams, B., Craig, I.W., Telang, F., Biegon, A., Wang, G.J., Fowler, J.S., and Volkow, N.D. (2009). Neural Mechanisms of Anger Regulation as a Function of Genetic Risk for Violence. Emotion 9, 385-396.
Cohen-Woods, S., Gaysina, D., Craddock, N., Farmer, A., Gray, J., Gunasinghe, C., Hoda, F., Jones, L., Knight, J., Korszun, A., Owen, M.J., Sterne, A., Craig, I.W., McGuffin, P. (2009). Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder. Hum Mol Genet [E Pub ahead of print, 30 Jan].
Craig, I.W. and Halton, K.E. (2009). Genetics of human aggressive behaviour. Human Genetics 126, 101-113.
Gaysina, D., Cohen-Woods, S., Chow, P.C., Martucci, L., Schosser, A., Ball, H.A., Tozzi, F., Perry, J., Muglia, P., Craig, I.W., McGuffin, P., and Farmer, A. (2009). Association of the Dystrobrevin Binding Protein 1 Gene [DTNBP1] in a Bipolar Case-Control Study [BACCS]. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics 150B, 836-844.
Huezo-Diaz, P., Uher, R., Smith, R., Rietschel, M., Henigsberg, N., Marusic, A., Mors, O., Maier, W., Hauser, J., Souery, D., Placentino, A., Zobel, A., Larsen, E.R., Czerski, P.M., Gupta, B., Hoda, F., Perroud, N., Farmer, A., Craig, I., Aitchison, K.J., and McGuffin, P. (2009). Moderation of antidepressant response by the serotonin transporter gene. British Journal of Psychiatry 195, 30-38.
Green, E.K., Grozeva, D., Raybould, R., Elvidge, G., Macgregor, S., Craig, I., Farmer, A., McGuffin, P., Forty, L., Jones, L., Jones, I., O’Donovan, M.C., Owen, M.J., Kirov, G. and Craddock, N. (2009). P2RX7: A Bipolar and Unipolar Disorder candidate susceptibility gene? Am J Med Genet B Neuropsychiatr Genet [E Pub ahead of print, 21 Jan].
Meaburn, E.L., Fernandes, C., Craig, I.W., Plomin, R., and Schalkwyk, L.C. (2009). Assessing Individual Differences in Genome-Wide Gene Expression in Human Whole Blood: Reliability Over Four Hours and Stability Over 10 Months. Twin Research and Human Genetics 12, 372-380.
Sugden K., Tichopad, A., Khan, N., Craig, I.W. and D’Souza, U. (2009). Genes within the serotonergic system are differentially expressed in human brain. BMC Neuroscience 2009, 10:50 doi:10.1186/1471-2202-10-50.
Uher, R., Huezo-Diaz, P., Perroud, N., Smith, R., Rietchel, M., Mors, O., Hauser, J., Maier, W., Kozel, D., Henigsberg, N., Barreto, M., Placentino, A., Dernovsek, M.Z., Schulze, T.G., Kalember, P., Zobel, A., Czerski, P.M., Larsen, E.R., Sourey. D., Giovannini, C., Gray, J.M., Lewis, C.M., Farmer, A., Aitchison, K.J., McGuffin, P., and Craig, I. (2010). Genetic predictors of response to antidepressants in the GENDEP project. The Pharmacogenomics Journal, accepted for publication.
Schosser, A., Cohen-Woods, S., Gaysina, D., Chow, P.C., Martucci, L., Farmer, A., Korszun, A., Gunashinghe, C., Gray, J., Jones, L., Craddock, N., Owen, M.J., Craig, I.W., McGuffin, P. (2010). NRG1 Gene in Recurrent Major Depression: No Association in a Large-Scale Case-Control Association Study. Am J Med Genet Part B 153B, 141-147.
Craig, I.W. and Halton, K.E. Genetics of human aggressive behaviour. Encyclopedia of Life Sciences. In press.
last updated: Saturday, April 17, 2010